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[Conference Item]

Those who are interested in the public mood, including politicians and economists, comment that the public are becoming ever more sceptical about many things, but health risk information should not be one of them. If health risk information is perceived by the public as ‘just another scary story’, or ‘more of the same we heard last month’, then the ability of risk messages to convey... [Thesis or Dissertation]

Background: Enteral nutrition is one method of delivering nutrition to intubated patients. There are several issues that prevent optimal delivery of the prescribed enteral nutrition goal rates. The measurement of the patient's gastric residual volume (GRV) may demonstrate tolerability, or intolerability, of enteral nutrition. Identifying a safe GRV, at which to accept and continue enteral...

Background: Enteral nutrition is one method of delivering nutrition to intubated patients. There are several issues that prevent optimal delivery of the prescribed enteral nutrition goal rates. The measurement of the patient's gastric residual volume (GRV) may demonstrate tolerability, or intolerability, of enteral nutrition. Identifying a safe GRV, at which to accept and continue enteral...

Professional ethics and legal competencies require midwives practising in New Zealand to provide care for childbearing women in a partnership characterised by continuity, equality, mutual respect, trust, shared responsibility and decision making. New Zealand is culturally and legislatively a bi-cultural environment and the cultural safety of Maori (indigenous peoples) are prioritised within... [Thesis or Dissertation]

Professional ethics and legal competencies require midwives practising in New Zealand to provide care for childbearing women in a partnership characterised by continuity, equality, mutual respect, trust, shared responsibility and decision making. New Zealand is culturally and legislatively a bi-cultural environment and the cultural safety of Maori (indigenous peoples) are prioritised within... [Thesis or Dissertation]

The operation of extrafascial excision dissects directly on the rectal fascia propria to remove the rectum and mesorectum within an intact fascial envelope. The studies contained in this thesis revolve around the recent finding that if a rectal cancer is contained within the fascia propria and the rectum is removed by extrafascial excision then local recurrence of the cancer will be... [Thesis or Dissertation]

This thesis examines the place of rehabilitation and reintegration in the criminal justice system. The aim of the research was to ascertain whether current law, policy and practice are conducive to the rehabilitation and reintegration of offenders and the reduction of recidivist offending. As research shows that offenders who are able to obtain and retain employment are less likely to... [Thesis or Dissertation]

[Thesis or Dissertation]

The metabolic responses to trauma are well characterized and there is growing evidence supporting an important role for cytokines in its pathogenesis. Interleukin-1 (IL-1), Interleukin-6 (IL-6), and Tumour necrosis factor (TNF) are synthesized in the brain, and other tissues, in trauma. In order to test the hypothesis that these cytokines play an important role in the metabolic responses... [Thesis or Dissertation]

This volume contains a series of linking chapters that follow the evolution of percutaneous intervention from conventional balloon angioplasty in the early to mid 1990s to stent implantation which has now become standard practice. It describes contributions to the extension of clinical situations in which percutaneous intervention has been found to be efficacious as well as refinements in... [Thesis or Dissertation]

Background, hypotheses and aims Poor fetal growth is associated with increased perinatal morbidity and mortality. Recently the topic of poor fetal growth has generated considerable research interest, as numerous epidemiological studies have demonstrated that small size at birth is also associated with increased risks of adult cardiovascular diseases and non-insulin dependent diabetes Antenatal... [Thesis or Dissertation]

The nutritional assessment of patients awaiting major abdominal surgery is important. It has been shown that malnutrition is common in such patients, but is often unrecognized. Because of the widespread availability of safe forms of nutritional therapy the task of identifying patients who warrant this therapy has become more urgent. However, current techniques used for the identification of... [Thesis or Dissertation]

Low molecular weight (LMW) proteins pass easily through the glomerular filter and are almost completely reabsorbed by the proximal renal tubule in health. An increase in their urinary excretion implies failure of reabsorption and may signal tubular dysfunction. β2-microglobulin (B2M) is a sensitive marker of tubular dysfunction, but is unstable in acid urine, whilst only limited data are... [Thesis or Dissertation]

Morphine is an effective potent analgesic. However the side effects of nausea, constipation and sedation are seen frequently. Respiratory depression is not such a common problem clinically but is the most potentially dangerous toxicity. An analgesic inducing equivalent analgesic potency without these toxicities would be particularly valuable. Morphine 6-glucuronide (M6G), one of the major... [Thesis or Dissertation]

The primary object of this thesis was to investigate aspects of empirically-measured, anaesthesia-induced electroencephalographic (EEG) changes that could be explained by network models of cortical interactions. The thesis consists of a collection of various theoretical and clinical papers in three sections: (a) A background section summarizing previous relevant published works on the molecular... [Thesis or Dissertation]

New generation T cell assays offer hope in the diagnosis of Mycobacterium tuberculosis infection and disease. We assessed the ELISPOT assay using cross-sectional and longitudinal studies and a natural gradient of M. tuberculosis exposure by sleeping proximity to a tuberculosis (TB) case in The Gambia. Two antigens, ESAT-6 and CFP-10 (EC), were compared to purified protein derivative (PPD) by... [Thesis or Dissertation]

CI-921, an analogue of the antileukaemic agent amsacrine, was produced in an attempt to develop a cytotoxic agent with a broader spectrum of activity. CI-921 was selected for clinical trial on the basis of superior in vivo and in vitro solid tumour activity. Sixteen patients with histologically documented cancer for which there was no conventional cytotoxic treatment were entered into a phase I... [Thesis or Dissertation]

Recent studies have demonstrated that 84% of women suffering from unexplained pelvic pain have dilated pelvic veins. Such appearances are generally considered to be evidence of ‘pelvic congestion’. Venographic studies of women without pain did not show these appearances. Management of pelvic congestion is considered difficult as there are few therapies currently available. Psychotherapy has... [Thesis or Dissertation]

The continued loss of protein from patients with severe sepsis, trauma or cancer cachexia, which occurs despite the provision of adequate calories and nitrogen, remains a challenge for surgeons and intensivists involved in their care. Prolonged loss of protein may impair cardiopulmonary and immune function and wound healing, and so its effective treatment may represent a considerable clinical... [Thesis or Dissertation]

Short-term variability in cerebral blood flow velocity (CBFV) in the VLBW infant largely relates to respiratory influence. Extreme variability may be a poor prognostic indicator. Few have studied cohorts of babies in this regard. I sequentially studied a consecutive cohort of unselected VLBW infants, to determine the frequency of respiratory influence on CBFVV and to identify factors associated... [Thesis or Dissertation]

Patients suffering from Inflammatory Bowel Disease (IBD) as a group uniformly suffer from nutritional problems. Nevertheless the extent, severity and clinical significance of Protein Energy Malnutrition (PEM) in the various clinical presentations of these diseases remains unclear. In particular little is known of the nutritional status of the ambulatory patient with IBD. Confusion still exists... [Thesis or Dissertation]

Whole document restricted until 11/2014, but available by request, use the feedback form to request access.Perinatal hypoxic ischaemic injury is an important cause of both neonatal death and long-term disability. The sequence of resuscitation followed by a latent phase then a secondary cascade of injury is well documented. This thesis covers key steps toward the utilization of selective hypothermia as an intervention during the latent phase to ameliorate the secondary injury and improve subsequent... [Thesis or Dissertation]

Restricted Item. Print thesis available in the University of Auckland Library or available through Inter-Library Loan. In New Zealand (NZ) asthma mortality rates are higher than in any other developed country studied, and hospital admission rates for asthma are among the highest. Within NZ, both mortality and hospital admission rates for asthma are higher among Polynesians than among Europeans.... [Thesis or Dissertation]

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