Modelling NFAT Cycling Sensitivity in the Cardiac Myocyte

Author: Cooling, Michael; Hunter, Peter; Crampin, Edmund

Date: 2007-10-01

Type: Conference poster

Link to this item using this URL: http://hdl.handle.net/2292/8577

The University of Auckland Library

Abstract

The transcription factor NFAT acts as a signal integrator for a number of signal transduction pathways in cardiac myocytes that initiates gene expression in the disease Pathological Cardiac Hypertrophy[1]. Here we develop a quantitative mathematical model of the cytoplasmicnuclear-cytoplasmic cycling of NFAT in response to calcium signals in the cardiac myocyte

Citation: ["The Eight International Conference of Systems Biology. 01 Oct 2007"]

Copyright: https://researchspace.auckland.ac.nz/docs/uoa-docs/rights.htm