68 results for Book, 2007

  • Informing New Zealand: Libraries, archives and records = Hei puna whakamohio mo Aotearoa: Whare pukapuka, puranga korero, whare taonga.

    (2007)

    Book
    Open Polytechnic

    Informing New Zealand brings together accounts of the background and current work of the diverse range of orgaisatiions that form the core of information management in New Zealand.

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  • Astronomy Aotearoa : NCEA level 1.

    Shaw, R. (2007)

    Book
    Open Polytechnic

    Astronomy Aotearoa is the base resource and student guide for NCEA astronomy. It introduces key topice and motivates students. The books will also attract anyone with an interest in science and New Zealand endeavour.

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  • Accounting practices: The New Zealand context.

    McIntosh, R. (2007)

    Book
    Open Polytechnic

    Written for students studying for the New Zealand Diploma of Business paper, Accounting Practices 501.

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  • Principles of accounting.

    Smart, M.; Awan, N.; Bourke, D. (2007)

    Book
    Open Polytechnic

    Principles of Accounting introduces students to the general principles and concepts of accounting, including budgeting and analysis and interpretation of financial reports. It has been written for first-year accountancy students studying for the New Zealand Diploma in Business, and this third edition has been updated and reorganised to closely follow the prescription for 400 Accounting Principles. It also meets the introductory accounting requirements for the New Zealand Institute of Management Diploma in Management and Advanced Diploma in Management, and the Australasian Institute of Banking and Finance Diploma.

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  • Professional accounting practices

    McIntosh, R. (2007)

    Book
    Open Polytechnic

    Details how to produce statements, journals and ledgers, calculate GST, inventory levels and depreciation.

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  • The Future of Tokelau: Decolonising Agendas 1975-2006

    Huntsman, Judith (2007)

    Book
    The University of Auckland Library

    A contemporary history tracing and explaining how the atolls of Tokelau were programmed by the New Zealand Government and the United Nations Decolonisation Committee to become "decolonised" and how Tokelau in a 2006 Referendum rejected their efforts. The study is based on documentary research in NZ Ministry of Foreign Affairs archives and the NZ National Archives, and on ethnographic research in Tokelau and among Tokelau people in New Zealand.

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  • Ruling Class Men : money, sex, power

    Donaldson, M; Poynting, Noel (2007)

    Book
    The University of Auckland Library

    What is it like to be a master of the universe? The authors have researched the desires and fears of the world’s most powerful men. The Murdochs, Packers, Kennedys, Agnellis and other men like them, directly determine the fates of thousands and influence the future of the world like no other people. Described as ‘sacred monsters’ by one of their own, they are carefully created to be what they are and to enjoy shaping the world in their own likeness. To learn about these often reclusive men, the authors extended the life-history technique to interrogate autobiographies, diaries and biographies and have created a composite picture, a collective portrait, of tycoons over three generations. The book carefully explores the childhoods, schooling, work and play, sexual activities, marriages and deaths of the wealthiest men who have ever lived. It exposes the nature of ruling-class masculinity itself.

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  • Lecture on Ethics: Introduction, Interpretation and Complete Text

    Wittgenstein, Ludwig (2007)

    Book
    The University of Auckland Library

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  • Provoziertes Schreiben - Drogen in der deutschsprachigen Literatur seit 1945

    Resch, Stephan (2007)

    Book
    The University of Auckland Library

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  • Selective targeting of apoptotic pathways in follicular lymphoma cells

    Wlodkowic, Donald (2007)

    Book
    The University of Auckland Library

    The seminal discovery that the BCL2 gene inhibits cell death rather than promotes cell proliferation gave the foundation for a nowadays widely appreciated theory that impaired tumor cell death is a decisive stage in a multi-step carcinogenesis. Recognition of the central role of mitochondria and Bcl-2 family members in the regulation and propagation of cell demise has, thus, recently uncovered novel targets for selective anti-cancer therapies. In this context, we have for the first time demonstrated monotherapeutic potential of a small molecule Bcl-2 antagonist, HA14-1, against follicular lymphoma (FL) cells with t(14;18) translocation and Bcl-2 overexpression. In agreement with others we have shown that cytotoxicity mediated by a small molecule Bcl-2 inhibitor HA14-1 in FL cells proceeds through rapid (4h) dissipation of the ∆Ψm, generation of ROS and caspase-dependent apoptosis. Moreover, we were first to prove the applicability of combinatorial treatment of HA14-1 and selected conventional chemotherapeutics (dexamethasone and doxorubicin) in FL cells. In the following work we investigated the quantitative relationship between ∆Ψm loss and caspase activation in HA14-1 treated cells. Employing both pharmacological inhibitor studies and novel state-of-the-art multiparametric flow cytometry assays, we revealed that following HA14-1 treatment caspase activation occurs solely as a consequence of mitochondrial breach. Additionally, we provided new evidence that HA14-1-evoked apoptosis appears to be at least partially PT-dependent. We also for the first time addressed the cell cycle specificity of HA14-1 action using multivariate flow cytometry approaches. As the interest in the role of ER and Golgi during induction/execution of apoptosis has been gaining momentum, they simultaneously attract growing appreciation in the development of novel anti-cancer therapies. Pertinent to the therapy of B-cell malignancies we report here for the first time the effects of an ER-Golgi transport inhibitor, Brefeldin A (BFA), alone and in combination with a small molecule Bcl-2 inhibitor HA14-1 or death receptor trigger, in the human FL cell lines bearing t(14;18) translocation. Of importance for future anti-cancer regimens, small molecule Bcl-2 antagonist, HA14-1 and agonistic anti-Fas mAb significantly enhanced BFA- mediated cytotoxicity and apoptosis, revealing novel and previously unexplored avenues to enhance ER-stress mediated cell killing in B-cell malignancies. Finally, as basic studies advance towards their ultimate translational goals there is a need for effective and rapid analytical methods allowing high-throughput detection of diverse cell demise modes. In this context patented SYTO® probes are gaining increasing interest as easy to use markers of apoptosis. Herein, applying the state-of-the-art multiparametric flow cytometry and multicolor cell imaging we identified for the first time different SYTO16 staining characteristics upon apoptotic and oncotic stimuli. We also tracked similarities and discrepancies between SYTO16 and ∆Ψm, sensitive probe, tertramethylrhodamine methyl ester (TMRM), demonstrating that stimulation with mitochondrial uncoupler FCCP and a small-molecule Bcl-2 inhibitor, HA14-1, induce distinct staining profiles with the decrease in TMRM fluorescence preceding the loss of SYTO16 fluorescence. To our knowledge this is the first report demonstrating such a distinct behavior of SYTO16 and TMRM and our data demonstrate that loss of SYTO16 is caspase-dependent, as is not a mere indicator of ∆ψm dissipation, postulated previously by some authors.

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  • Believing by faith: an essay in the epistemology and ethics of religious belief

    Bishop, John (2007)

    Book
    The University of Auckland Library

    Can it be justifiable to commit oneself ‘by faith’ to a religious claim when its truth lacks adequate support from one's total available evidence? After critiquing both Wittgensteinian and Reformed epistemologies of religious belief, this book defends a modest fideism that understands theistic commitment as involving ‘doxastic venture’ in the face of evidential ambiguity: practical commitment to propositions held to be true through ‘passional’ causes (causes other than the recognition of evidence of or for their truth). It is argued that the justifiability of religious faith-ventures is ultima ...

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  • Kant on Judgement

    Wicks, Robert (2007)

    Book
    The University of Auckland Library

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  • International Encyclopaedia of Laws: Conflict of Laws: South Africa

    Schoeman, Elsabe; Roodt, HC (2007)

    Book
    The University of Auckland Library

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  • Task Scheduling for Parallel Systems

    Sinnen, Oliver (2007)

    Book
    The University of Auckland Library

    Extending beyond the classic approach by focusing on more advanced, accurate, and realistic models, this book investigates the concepts and techniques of task scheduling by developing a consistent and unifying theoretical framework.

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  • Herbal Medicines.

    Barnes, Joanne; Anderson, LA; Phillipson, JD (2007)

    Book
    The University of Auckland Library

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  • Being sociological

    Curtis, B; Carter, I; Matthewman, Steven; Manicas, PT; Bedggood, D; West-Newman, CL; Vodanovich, I; Sullivan, M; McIntosh, T; Shaw, R (2007-05-29)

    Book
    The University of Auckland Library

    Being Sociological is a concise and original thematic introduction to sociology that will help lecturers inspire their students and act as a springboard into the wider literature.

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  • Carbon neutral by 2020: How New Zealanders can tackle climate change

    Harré, Niki; Atkinson, Q (2007-01)

    Book
    The University of Auckland Library

    This book offers a positive response by presenting solutions from a range of New Zealand experts, all of whom show how we can rethink our current practices, mobilise people and put in place new ways of doing things that will help create a ...

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  • Pragmatics

    Huang, Yan (2007)

    Book
    The University of Auckland Library

    "This introduction to pragmatics - the study of language in use - provides an authoritative, up-to-date, and comprehensive account of its central topics and a guide to the latest research. It opens with a discussion of the scope, meaning, and history of pragmatics from Aristotle to the present. It shows how the subject relates to the study of semantics, syntax, and sociolinguistics and to such fields as the philosophy of language, linguistic anthropology, and artificial intelligence."--BOOK JACKET.

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  • Jade Taniwha: Māori-Chinese Identity and Schooling. Auckland: Rautaki.

    Lee, Jennifer (2007)

    Book
    The University of Auckland Library

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  • Understanding utilitarianism

    Mulgan, Timothy (2007-07-25)

    Book
    The University of Auckland Library

    Beyond ethics or morality, utilitarian assumptions and arguments abound in modern economic and political life, especially in public policy. Understanding Utilitarianism presents utilitarianism as a living tradition.

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