1,808 results for Book

  • Learning and Behaviour - Psychology 203 Course book

    Davison, M; Jones, BM; Elliffe, D; Krageloh, C; Podlesnik, Christopher (2011)

    Book
    The University of Auckland Library

    "General impressions are never to be trusted. Unfortunately, when they are of long standing, they become fixed rules of life and assume a prescriptive right not to be questioned. Consequently, those who are not accustomed to original enquiry entertain a hatred and horror of statistics. They cannot endure the idea of submitting sacred impressions to cold-blooded verification. But it is the triumph of scientific men [sic] to rise superior to such superstitions, to desire tests by which the value of beliefs may be ascertained, and to feel sufficiently masters of themselves to discard contemptuously whatever may be found untrue."

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  • Company Law in New Zealand

    Watts, PG; Campbell, N; Hare, Christopher (2011)

    Book
    The University of Auckland Library

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  • Political marketing: principles and applications

    Lees-Marshment, Jennifer (2009)

    Book
    The University of Auckland Library

    First textbook in political marketing; utilising research case studies from authors around the world; and a wide range of political marketing theory; the first comprehensive political marketing textbook.

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  • Zehn Jahre auf den Inseln der Südsee 1887-1897: Aus dem Tagebuch der Paula David/Ten Years in the Islands of the South Seas 1887-1897: From the Diary of Paula David

    David, P (2011)

    Book
    The University of Auckland Library

    This is a bilingual German-English edition of Paula David's German diaries of her time in Tonga and Samoa 1887-1897, and includes annotations and background chapters on the Leser family, the German connection with Tonga, and reproductions of photos of scenes of Tonga and Samoa from her photograph album.

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  • Fontane's Landscapes

    Bade, James (2009)

    Book
    The University of Auckland Library

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  • Conceptions of Assessment: Understanding What Assessment Means to Teachers and Students

    Brown, Gavin (2008)

    Book
    The University of Auckland Library

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  • Global political marketing

    Lees-Marshment, Jennifer (2010)

    Book
    The University of Auckland Library

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  • Sea Devil: Count Felix von Luckner in New Zealand & the Pacific

    Bade, James (2006)

    Book
    The University of Auckland Library

    Reviewed in Journal of Fellowship of Samoan Specialists, December 2006. Book of the Week, National Programme, Radio NZ, 3 December 2006

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  • Global and local art histories

    Jeffery, Celina (2007-08)

    Book
    The University of Auckland Library

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  • Images of Thought

    Minissale, Gregory (2006)

    Book
    The University of Auckland Library

    This book does not tell a story, at least not the kind of story of characters and events that has been told in art history many times. Instead, it tries to understand how visual language works using a number of paintings produced in India, and to a lesser extent, Iran. ...

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  • Cosa succede a Fraus? Sardegna e mondo nel racconto di Giulio Angioni

    Manai, Franco (2006)

    Book
    The University of Auckland Library

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  • Realizing the power of professional learning

    Timperley, H (2011)

    Book
    The University of Auckland Library

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  • Group Architects: Towards a New Zealand Architecture

    Gatley, J (2010)

    Book
    The University of Auckland Library

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  • Bill Culbert : making light work / Ian Wedde.

    Wedde, Ian (2009)

    Book
    The University of Auckland Library

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  • Education, Social Justice & the Legacy of Deakin University: Reflections of the Deakin Diaspora

    Tinning, Richard (2011)

    Book
    The University of Auckland Library

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  • Teaching Health and Physical Education in Australian Schools

    Tinning, Richard; McCuaig, L; Hunter, L (2006)

    Book
    The University of Auckland Library

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  • Nga Kaupapa Here: Connections and Contradictions in Education

    (2008)

    Book
    The University of Auckland Library

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  • Re-thinking drowning risk: The role of water safety knowledge, attitudes, and behaviours in the aquatic recreation of New Zealand youth

    Moran, Kevin (2009)

    Book
    The University of Auckland Library

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  • Selective targeting of apoptotic pathways in follicular lymphoma cells

    Wlodkowic, Donald (2007)

    Book
    The University of Auckland Library

    The seminal discovery that the BCL2 gene inhibits cell death rather than promotes cell proliferation gave the foundation for a nowadays widely appreciated theory that impaired tumor cell death is a decisive stage in a multi-step carcinogenesis. Recognition of the central role of mitochondria and Bcl-2 family members in the regulation and propagation of cell demise has, thus, recently uncovered novel targets for selective anti-cancer therapies. In this context, we have for the first time demonstrated monotherapeutic potential of a small molecule Bcl-2 antagonist, HA14-1, against follicular lymphoma (FL) cells with t(14;18) translocation and Bcl-2 overexpression. In agreement with others we have shown that cytotoxicity mediated by a small molecule Bcl-2 inhibitor HA14-1 in FL cells proceeds through rapid (4h) dissipation of the ∆Ψm, generation of ROS and caspase-dependent apoptosis. Moreover, we were first to prove the applicability of combinatorial treatment of HA14-1 and selected conventional chemotherapeutics (dexamethasone and doxorubicin) in FL cells. In the following work we investigated the quantitative relationship between ∆Ψm loss and caspase activation in HA14-1 treated cells. Employing both pharmacological inhibitor studies and novel state-of-the-art multiparametric flow cytometry assays, we revealed that following HA14-1 treatment caspase activation occurs solely as a consequence of mitochondrial breach. Additionally, we provided new evidence that HA14-1-evoked apoptosis appears to be at least partially PT-dependent. We also for the first time addressed the cell cycle specificity of HA14-1 action using multivariate flow cytometry approaches. As the interest in the role of ER and Golgi during induction/execution of apoptosis has been gaining momentum, they simultaneously attract growing appreciation in the development of novel anti-cancer therapies. Pertinent to the therapy of B-cell malignancies we report here for the first time the effects of an ER-Golgi transport inhibitor, Brefeldin A (BFA), alone and in combination with a small molecule Bcl-2 inhibitor HA14-1 or death receptor trigger, in the human FL cell lines bearing t(14;18) translocation. Of importance for future anti-cancer regimens, small molecule Bcl-2 antagonist, HA14-1 and agonistic anti-Fas mAb significantly enhanced BFA- mediated cytotoxicity and apoptosis, revealing novel and previously unexplored avenues to enhance ER-stress mediated cell killing in B-cell malignancies. Finally, as basic studies advance towards their ultimate translational goals there is a need for effective and rapid analytical methods allowing high-throughput detection of diverse cell demise modes. In this context patented SYTO® probes are gaining increasing interest as easy to use markers of apoptosis. Herein, applying the state-of-the-art multiparametric flow cytometry and multicolor cell imaging we identified for the first time different SYTO16 staining characteristics upon apoptotic and oncotic stimuli. We also tracked similarities and discrepancies between SYTO16 and ∆Ψm, sensitive probe, tertramethylrhodamine methyl ester (TMRM), demonstrating that stimulation with mitochondrial uncoupler FCCP and a small-molecule Bcl-2 inhibitor, HA14-1, induce distinct staining profiles with the decrease in TMRM fluorescence preceding the loss of SYTO16 fluorescence. To our knowledge this is the first report demonstrating such a distinct behavior of SYTO16 and TMRM and our data demonstrate that loss of SYTO16 is caspase-dependent, as is not a mere indicator of ∆ψm dissipation, postulated previously by some authors.

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  • Student perspectives on assessment

    (2009-11-30)

    Book
    The University of Auckland Library

    Assessment for learning is meant to engage, motivate, and enable students to do better in their learning. However, how students themselves perceive assessments (both high-stakes qualifications and low-stakes monitoring) is not well understood. This volume collects research studies from Europe, North and South America, Asia, and New Zealand that have deliberately focused on how students in primary, secondary, and tertiary education conceive of, experience, understand, and evaluate assessments. Assessment for learning has assumed that formative assessments and classroom practices would be an unqualified success in terms of student learning outcomes. Making use of a variety of qualitatively interpreted focus groups, observations, and interviews and factor-analytic survey methods, the studies collected in this volume raise doubts as to the validity of this formulation. We commend this volume to readers hoping to stimulate their own thinking and research in the area of student assessment. We believe the chapters will challenge researchers, policy makers, teacher educators, and instructors as to how assessment for learning can be implemented.

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