63 results for Patent

  • Model Assisted Planning of Medical Imaging

    Cowan, BR; O'donnell, T; Young, Alistair (2005-01-13)

    Patent
    The University of Auckland Library

    A method (600) and system (700) for medical image acquisition are provided, where the method (600) includes acquiring an image of the region of interest (610), acquiring a model for a region of interest (620), and fitting the model to the image (630); the system (700) includes a modeling unit for modeling a region of interest (770); an acquisition unit in signal communication with the modeling unit for acquiring an image of the region of interest (732); and a fitting unit in signal communication with the acquisition unit for fitting the model to the image (780).

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  • Effects of Glycyl-2-methylprolylglutamate on Neurodegeneration

    Gluckman, Peter; Thomas, GB; Guan, J; Dragunow, M; Anand, Ashmit; Kerlero de Rosbo, N; Sieg, F; Brimble, Margaret (2007-12-27)

    Patent
    The University of Auckland Library

    This invention provides analogs and peptidomimetics of glycyl-L-prolyl-L-glutamic acid (GPE). In particular, this invention relates to GPE analogs and peptidomimetics that are anti-apoptotic, anti-necrotic and have neuroprotective effects. These agents are useful in treating neurodegeneration and behavioural disorders caused by toxins, traumatic brain injury and autoimmune disorders of the brain, such as multiple sclerosis and in reducing seizures.

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  • Neural Regeneration Peptides and Methods for their Use

    Sieg, F; Brimble, Margaret; Muir, Victoria (2010-05-27)

    Patent
    The University of Auckland Library

    Embodiments of this invention include novel peptides that can promote survival of neurons and other cell types. Other embodiments of this invention include the methods for the use of peptides to promote neuronal migration, neurite outgrowth, neuronal proliferation, neural differentiation, neuronal survival and/or trophoblast proliferation, trophoblast migration and trophoblase survival. NRP compounds may be administered directly to a subject or to a subject's cells by a variety of means including orally, intraperitoneally, intravascularly or indirectly via a replicable vehicle. NRP compounds can be formulated into pharmaceutically acceptable dosage forms for therapeutic use. Kits containing pre-determined doses of an NRP can be used to conveniently store, prepare and administer an NRP to a subject in need thereof.

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  • Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate

    Gluckman, Peter; Brimble, Margaret; Wilson, D; Tortella, FC; Williams, AJ; Xi-Chun, ML; Hartings, JA; Gryder, D (2010-05-11)

    Patent
    The University of Auckland Library

    Aspects of this invention include the use of G-2MePE to treat patients with brain injury characterized by non-convulsive seizures. G-2MePE is useful in treating brain injuries caused by traumatic brain injury, stroke, hypoxia/ischemia and toxic injury.

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  • Tinnitus treatment system and method

    Searchfield, Grant; Kobayashi, Kei; Irving, Samuel (2011)

    Patent
    The University of Auckland Library

    A tinnitus masking system for use by a person having tinnitus. The system comprises a sound delivery system having left and right ear-level audio delivery devices and is configured to deliver a masking sound to the person via the audio delivery devices such that the masking sound appears to originate from a virtual sound source location that substantially corresponds to the spatial location in 3D auditory space of the source of the tinnitus as perceived by the person. The masking sound being represented by left and right audio signals that are converted to audible sound by the respective audio delivery devices.

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  • Directly photodefinable polymer compositions and methods thereof

    Elce, E; Bell, A; Knapp, B; Ng, H; Rhodes, LF; Shick, R; Zhang, W; Dimenna, W; Jayaraman, S; Jin, Jianyong; Puthenkovilakom, RR; Ravikiran, R; Wu, X; Takeuchi, E (2011)

    Patent
    The University of Auckland Library

    A polymer includes a first type of repeat unit represented by Formula I, where X is selected from -CH2-, -CH2-CH2-, or -O-; m is an integer from 0 to about 5; and where for the first type of repeat unit one of R1, R2, R3, and R4 is one of a maleimide containing group and for the second type of repeat unit one of R1, R2, R3, and R4 is a hindered aromatic group, a C8 or greater alkyl group, a C4 or greater halohydrocarbyl or perhalocarbyl group, a C7 or greater aralkyl group, or a heteroatom hydrocarbyl or halohydrocarbyl group.

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  • Polypeptides and Polynucleotides for Artemin and related Ligands, and Methods of Use Thereof

    Liu, Dongxu; Lobie, Peter (2008)

    Patent
    The University of Auckland Library

    The invention encompasses polypeptides, polynucleotides, and antibodies, for Artemin and related ligands, including Persephin (PSPN). The invention also encompasses expression vectors and host cells for producing these polypeptides, polynucleotides, or antibodies. The invention further encompasses diagnostics and therapeutics, especially for cancer, and particularly breast cancer, colon cancer, prostate cancer, endometrial cancer, lung cancer, stomach cancer, liver cancer, and others, comprising one or more of the disclosed polypeptides, polynucleotides, antibodies, expression vectors, host cells, or compositions thereof. Particularly encompassed are inhibitors of Artemin and/or related ligands, and uses for these inhibitors.

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  • Improvements for Cochlear Implants

    Bradley, AP; Petoe, Matthew; Wilson, WJ (2010)

    Patent
    The University of Auckland Library

    The invention relates to a method of generating a place-frequency map for accurate positioning of a cochlear implant whereby the place-frequency map is used to relate a physical position of the cochlear implant to a tonotopic map of the basilar membrane/spiral ganglion. The invention also relates to a method of electrically positioning of an already inserted cochlear implant within the cochlea to provide stimuli to only the parts of the cochlea that have reduced or no residual hearing.

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  • Transcription Factors

    Bloksberg, LN; Bryant, C; Connett, MB; Emerson, SJ; Frost, MJ; Forster, RLS; Grigor, M; Higgins, C; Lasham, Annette; Lund, ST; Magusin, A; Phillips, J; Puthigae, S; Veerakone, S; Westwood, C; Gause, K; Wood, M; Havukkala, I; Rottmann, WH (2009-03-24)

    Patent
    The University of Auckland Library

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  • 5-Substituted-4-[(substituted phenyl)amino]-2-pyridone derivatives

    Black, Shannon; Kaufman, MD; Ortwine, DF; Plummer, MS; Quin, J; Rewcastle, Gordon; Shahripour, AB; Spicer, Julie; Whitehead, CE (2007)

    Patent
    The University of Auckland Library

    The present invention relates to 5-substituted-4-(substituted)phenylamino-2-pyridone derivatives, pharmaceutical compositions and methods of use thereof.

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  • Substituted pyrimidines and triazines and their use in cancer therapy

    Rewcastle, Gordon; Shepherd, Peter; Chaussade, C; Denny, William; Gamage, Swarnalatha (2009)

    Patent
    The University of Auckland Library

    Provided herein are substituted pyrimidine and triazine derivatives, including bicyclic pyrimidine derivatives, their pharmaceutical compositions, their preparation, and their use as agents or drugs for cancer therapy, either alone or in combination with radiation and/or other anticancer drugs. In one embodiment, the pyrimidine and triazine derivatives are morpholino-pyrimidine, morpholino-triazine, pyridyl-pyrimidine, and pyridyl-triazine derivatives which are selective irreversible inhibitors of the p110α isoform of PI3K.

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  • Pteridinones as kinase inhibitors

    Denny, William; Rewcastle, Gordon; Dobrusin, EM; Kramer, JB; McNamara, DJ; Showalter, HD; Toogood, PL (2007)

    Patent
    The University of Auckland Library

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  • Novel Saratan Polypeptides and Polynucleotides and Methods of Use Thereof

    Liu, Dongxu; Lobie, Peter (2008)

    Patent
    The University of Auckland Library

    The invention relates to Saratan polypeptides, polynucleotides, and antibodies. The invention also relates to expression vectors and host cells for producing these polypeptides, polynucleotides, or antibodies. The invention further relates to diagnostics and therapeutics, especially for cancer, and particularly breast cancer, comprising one or more of the disclosed polypeptides, polynucleotides, antibodies, expression vectors, host cells, or compositions thereof.

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  • Method and system of measuring charateristics of an organ

    Young, Alistair; Cowan, Brett (2006-12-26)

    Patent
    The University of Auckland Library

    The invention provides a method of measuring characteristics of an organ or part thereof from multiple images of the organ or part thereof, the method comprising the steps of defining the spatial position of at least two of the images; defining a reference model of the organ or part thereof scaled according to the distance between reference markers on the images; defining one or more boundary guide points associated with one or more images for which the spatial positions have been defined; converting the guide points to three-dimensional coordinates; defining an estimate model by fitting the reference model to the guide points; and calculating the characteristics from the estimate model. The invention also provides a system and a computer program for measuring characteristics of an organ or part thereof of a subject from multiple images of the subject's organ or part thereof.

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  • Controlled needle-free transport

    Hunter, IW; Taberner, Andrew; Hemond, BD; Wendell, DM; Ball, NB; Hogan, NC

    Patent
    The University of Auckland Library

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  • Surface Injection Device

    Hunter, IW; Taberner, Andrew; Hemond, BD; Wendell, Dawn; Ball, NB; Hogan, NC

    Patent
    The University of Auckland Library

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  • Diagnostically and audibly responsive computer learning memory game and system provided therefor

    Dowrick, Peter (2006)

    Patent
    The University of Auckland Library

    A diagnostically and audibly responsive computer learning memory game works with small children and other persons in teaching them to read. Square or rectangular tiles to be uncovered are displayed upside down, concealing words to be matched with words or words to be matched with phrases or visual pictures or audible sounds, objective is to find matching cards. The computer game matches the cards or tiles with sight words that the user is learning to read from a word list. The user must remember where a correct word of the word pairs is located. The user must read word orally, if not, the computer will prompt the user with a clue (such as the beginning sound of a word) until the user answers. If nothing is heard, the user is told the answer. The system has a built-in recording of a library of selected words, phrases, pictures or audible sounds. The computer can sense that user is silent (with a default of no sound). If a wrong word is uttered, the system can remain silent or correct..

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  • Selection of animals for desired milk and/or tissue profile

    Lehnert, K; Berry, SD; Snell, Russell; Macgibbon, AKH; Spelman, R; Ankermist-Udy, A (2011)

    Patent
    The University of Auckland Library

    The present invention is directed to mutations in the DGAT1 gene that produce an advantageous milk, tissue and/or growth rate profile in animals carrying the mutations. The present invention is also directed to methods of identifying animals carrying the mutations in order to facilitate the selection of animals with altered milk, tissue and/or growth rate traits.

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  • Insecticidal Polypeptides and Methods of Use Thereof

    King, GF; Solld McFarland, B; Nicholson, GM; Gunning, Simon (2011-02-01)

    Patent
    The University of Auckland Library

    A family of insecticidal polypeptides expressed in the venom gland of spiders of the genera Atrax and Hadronyche have been described. Also included are polynucleotides and expression vectors encoding the polypeptides and insect viruses and cells expressing the polypeptides. Transgenic plants and insects expressing the insecticidal polypeptides are also described. The insecticidal polypeptides may be employed in methods and compositions for treating insects, insect larvae, and plants.

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  • Methods for producing neuronal cells and uses thereof

    Green, Colin; Sherwin, Trevor; Chang, CYA (2010)

    Patent
    The University of Auckland Library

    Methods for producing neuronal cells, methods of treating or preventing ophthalmic diseases or conditions or of promoting recovery from an ophthalmic therapy, and methods of treating or preventing neurological diseases or conditions or of promoting recovery from a neurological therapy are provided. The methods involving treating ophthalmic cells, particularly corneal cells, with insulin, epidermal growth factor and fibroblast growth factor 2 for a period sufficient to trans-differentiate the cells to neuronal cells.

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