Modelling NFAT Cycling Sensitivity in the Cardiac Myocyte

Author: Cooling, Michael; Hunter, Peter; Crampin, Edmund

Date: 2007-10-01

Type: Conference poster

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The University of Auckland Library


The transcription factor NFAT acts as a signal integrator for a number of signal transduction pathways in cardiac myocytes that initiates gene expression in the disease Pathological Cardiac Hypertrophy[1]. Here we develop a quantitative mathematical model of the cytoplasmicnuclear-cytoplasmic cycling of NFAT in response to calcium signals in the cardiac myocyte

Citation: ["The Eight International Conference of Systems Biology. 01 Oct 2007"]