15 results for 2000, Hogan, NC, Patent

  • Jet injector use in oral evaluation

    Hunter, IW; Chen, Y; Hogan, NC; Ruddy, BP (2012)

    Patent
    The University of Auckland Library

    A tooth treatment device includes a detector that detects a marker of oral health and a fluid ejector that ejects fluid against teeth in response to the detected marker. The device can include a housing configured to be held on hand, the fluid ejector being positioned at an end of the housing. The fluid may include a liquid, a medicant, a cleansing solution, cleaning particles, or any combination thereof. The medicant can include any combination of a chelating agent, fluoride, a fluorescent dye, a bacterial specific probe, and a biochemical specific biomarker. Further, the device can include a servo controller controlling pressure of ejected fluid in response to the detected marker and a sensed surface condition, latter including for example, a mechanical property of tissue. The device may include a pressure sensor that senses pressure of the fluid in the ejector. Also included may be a distance sensor that senses distance of the ejector from a tissue surface. The surface condition may be sensed using the sensed pressure, sensed distance, or any combination thereof. In some embodiments, the fluid ejector comprises a stationary magnet assembly providing a magnetic field and a coil assembly, slidably disposed with respect to the magnet assembly, the coil assembly driving ejection of the fluid jet. A method of tooth treatment includes detecting a marker of oral health and controlling ejection of a fluid jet against the tooth responsive to the detected marker. In some embodiments, detecting the marker includes detecting plaque and the ejection is controlled to clean the plaque. Detecting the marker can include collecting a sample from an oral cavity.

    View record details
  • Surface Injection Device

    Hunter, IW; Taberner, Andrew; Hemond, BD; Wendell, Dawn; Ball, NB; Hogan, NC (2010)

    Patent
    The University of Auckland Library

    A needle-free transdermal transport device (100) for non-axially transferring a substance across a surface of a biological body includes a reservoir (110) for holding a substance being transferred. A piston (105) is positioned within the device in communication with the reservoir (110) . An actuator (105) drives the piston (105) to expel the substance from the reservoir (110) . The reservoir (110) is in fluid communication with a nozzle (115) which includes at least one lateral aperture (145) through which the substance is expelled. Multiple lateral apertures (145) can result in a needle-free transfer across a selectable surface area. The depth and direction of an injection can be controlled by the parameters of the nozzle (115) . By providing a selective depth and direction, it is possible to inject a substance into a targeted biological layer, such as a cleavage plane to further promote coverage. A control source can be used to activate the device (100) . The device (108) can also include an optional power source (125) .

    View record details
  • Bi-directional motion of a lorentz-force actuated needle-free injector (NFI)

    Hunter, IW; Taberner, Andrew; Hogan, NC (2015-09-08)

    Patent
    The University of Auckland Library

    The present invention relate to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some embodiments, a powdered formulation is maintained in a first chamber. A bi-directional electromagnetic actuator is in communication with the chamber. The actuator, when activated, generates a pressure within the first chamber. The pressure results in mixing of the powdered formulation and a diluent in time for delivering into the biological body.

    View record details
  • Delivery of a solid body and/or a fluid using a linear Lorentz-force actuated needle-free jet injection system

    Hunter, IW; Taberner, Andrew; Hogan, NC (2014-09-02)

    Patent
    The University of Auckland Library

    A method for transferring a solid body across a surface of a biological body includes (i) applying an electrical input to a controllable electromagnetic actuator; (ii) producing with the electromagnetic actuator a mechanical force corresponding to the electrical input; and (iii) applying the mechanical force to a reservoir coupled at one end to a nozzle, the mechanical force producing a pressure within the reservoir, a magnitude of the pressure varying with the mechanical force and causing ejection of a fluid from the reservoir to drive the solid body into the biological body. A method for delivering a substance to a target body includes (i) positioning a needle-free injector proximate to a surface of the target body; (ii) injecting the substance into the target body; and (iii) while injecting, moving the needle-free injector along the surface, thereby sweeping the surface.

    View record details
  • Lorentz force linear actuator needle-free jet injection system to deliver solid and / or fluid

    Taberner, Andrew; Hunter, IW; Hogan, NC (2015-08-26)

    Patent
    The University of Auckland Library

    It means for conveying solids by the method of the surface of the organism, including (i) the electrical input applied to the controllable electromagnetic actuator; (ii) the actuator corresponding to said generated electrical machine with the electromagnetic input force; and (iii) applying mechanical force to the one end of the receptacle is coupled with the nozzle, the mechanical force generated pressure within the receptacle, with the magnitude of the pressure change and the mechanical force caused by the injection of fluid from the reservoir to drive solid into the organism. The method for delivering a substance to a target body, comprising (i) the needle-free injector near the surface of the target body; (ii) the substance injected into the target body; and (iii) at the same time injected, along the movement of the surface of the needle-free injector thus sweep the surface.

    View record details
  • Controlled needle-free transport

    Hunter, IW; Taberner, Andrew; Hemond, BD; Wendell, DM; Hogan, NC; Ball, NB (2015-03-31)

    Patent
    The University of Auckland Library

    A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.

    View record details
  • Controlled needle-free transport

    Hunter, IW; Taberner, Andrew; Hemond, BD; Wendell, DM; Ball, NB; Hogan, NC (2014-07-15)

    Patent
    The University of Auckland Library

    A needle-free transdermal transport device (100) for transferring a substance across a surface (155) of a biological body (150) includes a reservoir (113) for storing the substance, a nozzle (114) in fluid communication with the reservoir and a controllable electromagnetic actuator (125) in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly (105) and a moving coil assembly (104) . The coil assembly moves a piston (126) having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.

    View record details
  • Needle-free injector device with autoloading capability

    Hunter, IW; Hemond, BD; Wendell, DM; Hogan, NC; Taberner, Andrew; Ball, NB (2012-05-08)

    Patent
    The University of Auckland Library

    A needle-free transdermal transport device includes a chamber (900) for holding the substance to be injected, a nozzle (910) in fluid communication with the chamber, and a drug reservoir (950) for storing the substance to be transferred to the chamber. The needle-free transdermal transport device also includes a controllable magnet and coil electromagnetic actuator (242) in communication with the chamber. The actuator receives an electrical input and generates in response a force. The force then causes a needle-free transfer of the substance from the chamber to the biological body. The force is variable responsive to variations in the received input during actuation. The actuator draws the substance from the drug reservoir or alternatively, the substance can be pressurized from the drug reservoir into the chamber by a pressure source.

    View record details
  • Needle-free transdermal transport device

    Ball, NB; Hemond, BD; Hogan, NC; Hunter, IW; Taberner, Andrew; Wendell, DM (2009-08-16)

    Patent
    The University of Auckland Library

    needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.

    View record details
  • Surface injection device

    Taberner, Andrew; Hunter, IW; Hemond, BD; Wendell, DM; Ball, NB; Hogan, NC (2010-09-29)

    Patent
    The University of Auckland Library

    A needle-free transdermal transport device (100) for non-axially transferring a substance across a surface of a biological body includes a reservoir (110) for holding a substance being transferred. A piston (105) is positioned within the device in communication with the reservoir (110) . An actuator (105) drives the piston (105) to expel the substance from the reservoir (110) . The reservoir (110) is in fluid communication with a nozzle (115) which includes at least one lateral aperture (145) through which the substance is expelled. Multiple lateral apertures (145) can result in a needle-freetransfer across a selectable surface area. The depth and direction of an injection can be controlled by the parameters of the nozzle (115) . By providing a selective depth and direction, it is possible to inject a substance into a targeted biological layer, such as a cleavage plane to further promote coverage. A control source can be used to activate the device (100) . The device (108) can also include an optional power source (125) .

    View record details
  • Method and apparatus for extraction of a sample from a sample source

    Hunter, IW; Taberner, Andrew; Hogan, NC (2013-03-19)

    Patent
    The University of Auckland Library

    The present invention relate to a method and corresponding apparatus for extraction of a sample from a sample source. A fluid is injected into the sample source and the sample source is vibrated. A sample is withdrawn from the vibrated sample source and the sample source is evaluated by measuring one or more identifying parameters in the withdrawn sample.

    View record details
  • Controlled needle-free transport

    Hunter, IW; Taberner, Andrew; Hemond, BD; Wendell, DM; Hogan, NC; Ball, NB (2012-12-11)

    Patent
    The University of Auckland Library

    A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.

    View record details
  • Needle-free injector device with autoloading capability

    Hunter, IW; Hemond, BD; Wendell, DM; Hogan, NC; Taberner, Andrew; Ball, NB (2014-03-25)

    Patent
    The University of Auckland Library

    A needle-free transdermal transport device includes a chamber (900) for holding the substance to be injected, a nozzle (910) in fluid communication with the chamber, and a drug reservoir (950) for storing the substance to be transferred to the chamber. The needle-free transdermal transport device also includes a controllable magnet and coil electromagnetic actuator (242) in communication with the chamber. The actuator receives an electrical input and generates in response a force. The force then causes a needle-free transfer of the substance from the chamber to the biological body. The force is variable responsive to variations in the received input during actuation. The actuator draws the substance from the drug reservoir or alternatively, the substance can be pressurized from the drug reservoir into the chamber by a pressure source.

    View record details
  • Surface injection device

    Hunter, IW; Taberner, Andrew; Hemond, BD; Wendell, DM; Ball, NB; Hogan, NC (2010-10-27)

    Patent
    The University of Auckland Library

    Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules with specially designed jet passages at the injector's distal end.

    View record details
  • Injection methods using a servo-controlled needle-free injector

    Hemond, BD; Hunter, IW; Taberner, Andrew; Wendell, DM; Hogan, NC (2014-06-03)

    Patent
    The University of Auckland Library

    A method for injecting a substance through a biological body surface includes providing a needle-free transdermal transport device configured to inject the substance through the surface. The substance is injected into the biological body with the transport device while a parameter of the injection is sensed and a servo-controller is used to dynamically adjust at least one injection characteristic based on the sensed parameter. The substance is injected for (i) a first time period during which a first portion of a volume of the substance is injected at a first injection pressure, and (ii) a second time period during which a remainder of the volume of the substance is injected at a second injection pressure. A viscosity of the substance may be determined, and a pressure calculated for injecting the substance based on the viscosity. The substance may be injected with the transport device by using the calculated pressure.

    View record details