4,915 results for University of Otago, Thesis

  • Evolution Made Visible: The Worlds of Thomas Jeffery Parker (1850-1897) the Noted New Zealand Zoologist

    Crane, Rosemary Helen Beatrice (2015)

    Doctoral thesis
    University of Otago

    A biographical approach to the working life of Thomas Jeffery Parker FRS (1850-1897) provides scope for an in-depth investigation of how zoological knowledge became visible in late-nineteenth century New Zealand. A noted zoologist, Parker arrived in Dunedin in 1880 to a joint appointment as Professor of Biology in the University of Otago and Curator of the Museum. He had spent eight years working as demonstrator in Thomas Henry Huxley’s (1825-1890) laboratory in London. He brought with him a conviction that evolution provided the fundamental organising principle of biology. Once in Dunedin he set about making evolution visible. This study examines the various facets of Parker’s work that achieved this goal. I explore the lively debates arising from the public lectures he gave, in which he promoted evolution. In Dunedin, founded by Scottish Free Church Presbyterians in 1848, public interest in science-and-religion remained high throughout the late-nineteenth century. This study suggests that Parker’s own religious sensibilities lay between the agnosticism of Huxley and the faith of his Wesleyan father, the anatomist William Kitchen Parker (1823-1890). I also investigate Parker’s role in disseminating popular versions of biology, from the podium and through articles, to various audiences. His roles in the sociable side of scientific activities included organizing exhibits for conversaziones and international exhibitions. Parker’s efforts are placed within the context of Dunedin’s vibrant rational entertainment scene. Parker exchanged, bought, sold and collected specimens for the Otago University Museum in order to provide a comprehensive teaching collection. I appraise Parker’s previously little-understood role in museum collection building and explore his material practices in creating objects and their display according to evolutionary principles. Parker’s embryological studies of kiwi and phylogeny of the moa formed a major contribution to New Zealand biology. Methodologically speaking, he followed a traditional path of comparative anatomy. A close-reading of his more than forty papers of technically dense work reveal a conservative mind and a dedication to developmental morphology. Aware of changing epistemologies, he incorporated a statistical approach to his analyses. In this study, I suggest Parker created knowledge through drawing. Analysis of his illustrations reveals his concern with clear exposition. I show how the he used illustrations as part of the process of visual communication not simply as an adjunct. Generations of students learnt zoology using Parker’s system of ‘types’ a pedagogy he inherited from Huxley. They assimilated evolutionary principles via A Textbook of Zoology, which organized the animal kingdom in a typically late-nineteenth century progressive fashion. This two-volume book, co-authored with William Aitcheson Haswell (1854-1925) in Sydney and published posthumously, remains in print. An analysis of its creation shows how disciplinary shifts within zoology were fixed to the page. This study also uses Parker to explore wider concerns in the history of science. These include praxis and materiality, the popularization of science, the rise of the learned journal and broader aspects of print culture, and the geographic location of knowledge creation.

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  • Maximising the Potential of Existing Urban Infrastructure: Can Infrastructure Reuse Provide Successful Public Spaces?

    Kean, Gemma (2015)

    Masters thesis
    University of Otago

    There is great potential for innovative and creative public spaces beyond the traditional park or plaza to exist, yet this is still what most local authorities provide for in their public space policies. As cities intensify there is a need to provide additional public space in what may not have been considered to conventionally be a part of the public realm. Infrastructure is one example which can be used to provide additional public space through the adaptive reuse of a site, instead of abandonment or demolition when infrastructure is no longer required due to technological advancement. This research investigates whether the adaptive reuse of infrastructure can help create successful public spaces, and whether reuse can contribute towards improving the connectivity of an area. This is done using two case studies: Paddington Reservoir Gardens and the Ultimo Pedestrian Network in Sydney, New South Wales, Australia. The project explores whether there is too much focus on reusing the space with minimal adaptation, and the extent to which the planning processes enable or inhibit development, and allow for or discourage stakeholder involvement. The findings indicate that the adaptive reuse of infrastructure can provide interesting public spaces, however, success is dependent on the surrounding context. The two case studies employed in the research are vastly different. Despite this, the results show that infrastructural public spaces need to be active, provide for a range of users, and incorporate themes such as stickability and fine grain design to contribute positive outcomes to an urban environment.Often with infrastructure there is a risk of focusing too much on the preservation of heritage sites or making do with what already exists, instead of taking a greenfield approach to development. This can lead to spaces which are not integrated with the surrounds and which are not frequented or used as well as they could be. Further research needs to be undertaken to better understand the extent to which these particular public spaces-adaptively reused infrastructure differ to other spaces in the public realm.

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  • The Experience of Depression in the Tokelauan Culture in Two North Island Communities

    Loan, Iain Stuart (2015)

    Masters thesis
    University of Otago

    Background and Aims: The Tokelauan language lacks a word that corresponds to the western term ‘depression’. Furthermore, there is no research on the experience of depression in Tokelauans, and yet doctors continue to apply a western biomedical model of depression to Tokelauan patients and those from other Pacific cultures. This research aims to describe the experience of depression in Tokelauans and provide insight into its management. Better awareness of the symptoms and signs of depression as experienced by Pacific Islanders will enhance diagnosis and treatment of the illness by general practitioners. Method: Following extensive consultation with the Tokelauan community in Taupo, and using purposive stratified sampling, ten respondents contributed to this study. Semi-structured in depth interviews were performed and recorded verbatim. The transcripts of the interviews were thematically analysed using an immersion crystallisation technique, with further analysis to detect sub themes. Results: There is no specific word for depression in the Tokelauan language but an illness involving extraordinary sadness does exist. Ordinary sadness is regarded as just ‘part of life’ but extraordinary sadness can be classified as “unwellness” or “a burden". Tokelauans use several indicators to recognise someone with extraordinary sadness. The main indicator is isolation and withdrawal from family and community activities as well as absence from work and church. Tokelauan men are more likely to hold their feelings in and may indicate their unwellness with increased alcohol use or violent tendencies. For Tokelauans, privacy and pride are important cultural characteristics and these may be barriers to recognising sadness. The shame and loss of status associated with displaying sadness may also cause a person to hide his or her feelings. Often the smiling Tokelauan face becomes the mask that hides sadness. The main causes of extraordinary sadness are the changes caused by western influences on the Tokelauan culture and the stress of poverty and unemployment. The family, community and church are all important avenues for caring and for counselling the Tokelauan with extraordinary sadness. Discussion: This research documents some of the features of depression experienced by Tokelauans that are different from those that doctors may be trained to detect and manage using a western biomedical model. This research demonstrates the complexity of relationships between the patient, their illness and their culture that impacts on how the illness manifests. Similarly, this research indicates that therapy must have a holistic approach that includes the family, the community and that accounts for the patient’s spiritual beliefs. Te Vaka Atafaga is a metaphor for Tokelauan wellbeing involving a canoe. Its structure is representative of different components of health, and it provides a holistic model for the general practitioner involved in assessing and treating Tokelau Islanders with a possible depressive illness. The model does not exclude the use of western medical approaches, but it emphasises the need for social disharmony to be corrected to allow healing. Conclusion: The presentation and management of depression in Tokelauans may differ from that of other patients in a general practice setting. The Te Vaka Atafaga model provides the general practitioner with a tool to assess the different components that comprise health in the Tokelauan. A holistic approach involving the family, spirituality and correction of social factors along with palagi medicine is then necessary for treatment.

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  • Rib Fractures in Infants: Retrospective Survey of Fractures and Biomechanical Study.

    Blackburne, William Bligh (2015)

    Undergraduate thesis
    University of Otago

    Literature suggests that rib fractures are highly associated with abuse and the present understanding is that antero-posterior compression associated with the ‘shaken baby syndrome’ is their cause. However, this mechanism rests on a number of assumptions with little experimental data to support them. Recent work using a porcine model of fractures suggests that, in the case of lateral fractures this may be highly unlikely. This work shows a feasible alternate mechanism, that of blunt force trauma (BFT), for the cause of these lateral fractures. A piglet model is used and shows the ease with which ribs fracture as a result of BFT, compared to the difficulty of fracture seen previously in compressive injury. The initial development of a computational simulation of these ribs for use in injury scenarios is also outlined here. Secondly, skeletal surveys from New Zealand’s largest children’s care facility, Starship Hospital, were examined to give a picture of non-accidental injury (NAI) and how its patterns compare with accidental injury in New Zealand. It has been found that, as in foreign studies, there are a number of lesions highly associated with abuse and these include rib fractures, which are highly specific (97%) for NAI. Unusuallyhigh frequencies of lateral-type rib fractures (46.4%) were found and half the cases were found to be unilateral. This is not wholly in line with the currently accepted idea that rib fracture is due to antero-posterior compression, in which bilateral, posterior fractures are said to be most common. Overall, this work brings into question the traditional mechanism of rib fractures, provides a highly useful snapshot of abusive injury in NZ and also sets a strong foundation for future work.

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  • A Qualitative Exploration of the Barriers and Enablers to New Zealand City Councils Developing and Implementing Food and Nutrition Policy

    Gower, Jacinda Ruth (2015)

    Masters thesis
    University of Otago

    Background: Diet- related non communicable diseases and obesity are the biggest cause of ill health and mortality in New Zealand. Current government public health approaches do not appear to be effective in preventing non- communicable diseases and obesity as rates continue to increase. To combat the obesity epidemic research suggests government regulative policy which positively shapes food environments is needed. New Zealand’s current government’s ideologies’ reject public health nutrition regulative policy so are unlikely to be an effective agency to reduce obesity and non- communicable disease rates. Local Authorities have been proposed as an alternative government organisation that has the ability to positively influence local food environments through developing and implementing food and nutrition policy. However, no New Zealand Local Authorities have food and nutrition policy and currently, there is no research regarding Local Authority food and nutrition policy in a New Zealand context. Objective: This research project aims to explore factors which enable, hinder and influence New Zealand City Councils’ ability to develop and implement food and nutrition policy. Methods: This public health nutrition study is set in a policy context so qualitative research was used to explore the social and organisational factors influencing City Councils’ development of food and nutrition policy that supports health food environments. Semi- structured in depth telephone and face-to-face interviews were carried out with 21 participants with representation from each of the 12 City Councils and Auckland Council. These interviews consisted of nine core questions which were informed by a review of the literature. All interviews were recorded and selectively transcribed. A general inductive approach was used to thematically analyse the data to categorise it into six major themes underpinned by minor themes. A single case study design was used to portray emerging themes and to understand the context of New Zealand City Councils’ capacity to develop food and nutrition policy. Results: The results of this study identified an array of factors which influenced City Councils’ decision making to develop and implement food and nutrition policy to improve local food environments. Six overarching categories emerged as being prominent to explaining City Councils’ capacity to influence food environments. These categories are council resources, community influence, political factors, long term plans, national-level governments and research, case studies and nutrition guidelines. All of these influencing factors had the potential to act as a barrier or an enabler dependant on the local political environment. The main finding is City Councils’ have the capacity to develop food and nutrition policy when there is a widespread awareness and prioritisation of food environment issues in the agenda of three key groups; the community, elected members of council and council staff. Conclusion: New Zealand City Councils capacity to develop and implement food and nutrition policy is determined by a host of external, internal, national and local influence factors. A multi pronged approach of strong local political support, partnerships, credible champions and local or case study research are needed for food environment issues to be addressed by City Councils through the LTP and subsequent food and nutrition policy. To achieve this New Zealand’s public health community need to be active advocates at a City Council level and be involved with activating communities and raising awareness around food and nutrition issues.

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  • The role of cytoskeletal elements in the trafficking of KCa3.1 to the basolateral membrane of polarised epithelial cells

    Farquhar, Rachel (2015)

    Undergraduate thesis
    University of Otago

    The intermediate conductance, Ca2+-activated K+ channel (KCa3.1) is targeted to the basolateral membrane in polarized epithelia where it plays an essential role in promoting trans-epithelial ion transport. KCa3.1 is found in many tissues in the body and plays an important role in many physiological and pathological processes (e.g., regulation of salt and fluid transport in the gastrointestinal tract, atherosclerosis, sickle cell disease and asthma). Functional KCa3.1 must be targeted to the basolateral membrane, a process that is dependent upon proper cytoskeletal function. The cytoskeleton is comprised of actin and microtubule filaments. Actin filaments are comprised of polymerised G-actin monomers bound to form filamentous F-actin strands. Microtubules are long filamentous structures comprised of tubulin subunits, made from α-tubulin and β-tubulin monomers. This study examines the role of microfilaments and microtubules in the trafficking of KCa3.1 to the basolateral membrane of polarised epithelial cells. To address this, Fischer Rat Thyroid cells grown on filter inserts to form a confluent epithelium were stably transfected with the Biotin Ligase Acceptor Peptide (BLAP)-KCa3.1 construct. This construct allowed for the selective labeling of basolaterally expressed KCa3.1 using streptavidin. Selective labeling of membrane bound KCa3.1 allowed for the measurement of changes in KCa3.1 expression, in response to drugs that disrupt cytoskeletal elements, to reflect changes in KCa3.1 located on the basolateral membrane. This measure allowed for a direct correlation to be drawn between targeted disruption of specific cytoskeletal elements, e.g. microtubules and microfilaments, and expression of basolaterally-located KCa3.1. PCR was used to determine the mRNA expression levels of KCa3.1 in stably transfected cell lines and SDS-PAGE techniques were employed to investigate protein expression levels of KCa3.1. Western blotting was used to explore the effects of Cytochalasin D (Cyto D), Latrunculin A (Lat A), and Myosin Light Chain Inhibitor-7 (ML-7) which inhibit the function of actin (Cyto D, Lat A) and myosin light chain kinase (ML-7) respectively. Toxicity tests were performed to determine cell survival under a range concentrations of 0-20 μM (0, 3, 5 hr) for all three drugs with cell survival reduced with 20 μM at t = 5 hr for Cyto D and Lat A. Cyto D was administered over intervals of 0, 3 and 5 hr at 10 μM resulting in a decreased relative expression of KCa3.1 (compared to control) of 0.6±0.14 at t = 3 and further decrease in the expression of the channel at t = 5 hr with a relative expression of 0.12±0.035 (n = 5, p < 0.05). Lat A was also administered over intervals of 0, 3 and 5 hr at 10 μM causing a relative reduction in the expression of KCa3.1 at the basolateral membrane compared to the control. At t = 3 hr the expression of KCa3.1 was reduced to 0.7±0.065 and decreased to 0.3±0.049 at t = 5 hr (n = 4, p < 0.001). Finally, cells treated with microtubule inhibitor ML-7 showed a relative reduction in KCa3.1 expression of 0.55±0.12 at t = 3 hr, the expression was further decreased to 0.33±0.11 at t = 5 hr compared to the control. These data confirm that microtubules and microfilaments of the cytoskeleton are crucial in trafficking KCa3.1 to the basolateral membrane of polarised epithelial cells.

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  • "Too much 'yellow' in the melting pot?" : perceptions of the New Zealand Chinese, 1930-1960.

    Law, Penelope (1994)

    Undergraduate thesis
    University of Otago

    i, 65 leaves ; 30 cm. Includes bibliographical references (leaves 61-65). Typescript (photocopied)

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  • Diet of feral cats (Felis catus) in pastoral habitats of Canterbury, Otago and Southland : functional and numerical responses to rabbit availability

    Borkin, Kerry Maree (1999)

    Other thesis
    University of Otago

    v, 63 leaves : ill. ; 30 cm. Includes bibliographical references. "April 1999." University of Otago department: Zoology. University of Otago Wildlife Management Report no. 105.

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  • Nutritional assessment of older New Zealand adults living in rest homes in the lower South Island

    Greenwood, Daniel (2015)

    Masters thesis
    University of Otago

    Background: The increasing numbers of New Zealanders aged over 65 years will place a large burden on healthcare resources and rest home facilities around the country. Malnutrition is a major contributor to adverse health outcomes in the elderly, leading to higher mortality, morbidity and lower quality of life. There is very little information on the prevalence of malnutrition among New Zealand rest home residents, and there is not any information on the adequacy of nutrient intakes in this population. However, international data show very high rates of malnutrition and poor nutrient intakes amongst elderly residents in long-term low-level care. Objective: The specific aims of the study are in residents of two rest homes in the Lower South Island: i) To describe the prevalence of inadequate nutrient intakes; ii) To describe the prevalence of malnutrition risk; and, iii) To describe the prevalence of anaemia. Design: This cross-sectional study included 35 participants (14 men and 21 women), aged 69-102 years who lived in 2 rest homes in the lower South Island. Information on demographics, medical history, medications and supplement use were collected from medical notes. Malnutrition screening was done using two different screening tools- Mini Nutritional Assessment-Short Form and Malnutrition Universal Screening Tool. Cognitive function and mood were examined using the Clock Drawing Test and the Geriatric Depression Scale. Anthropometry measurements collected were; height, ulna length, weight, using standard protocols and body mass index (kg/m2) was calculated using average ulna length measurements. Dietary intake data were collected with 3-day food records, over 2 non-consecutive week days and one weekend day. Food intakes were matched to nutrient lines in the New Zealand Food Composition Tables to determine nutrient intakes. Nutrient intakes were then compared with current recommendations to estimate the prevalence of inadequate intakes. Blood and urine samples were taken for later analysis of biochemical nutritional status. Ethical approval was granted by the University of Otago Human Ethics Committee (Health) (H13/118). Results: The duration of stay in the rest homes ranged from 4 to 161 months (mean = 47months. Fifty percent of participants had a BMI over 25kg/m2, and 11% were underweight (BMI <20 kg/m2). Overall energy intakes were low, with 43% of men and 76% of women having suboptimal energy intakes (P=0.046 for differences between men and women). Sixty-three percent had inadequate protein intakes. Mean saturated fat intake was high, (16% of total energy intake), and average fibre intakes were low (19 g/day). All participants had suboptimal selenium and vitamin D intakes, although 83% of participants were on a monthly vitamin D supplement. Over 90% had inadequate intakes of calcium, magnesium, vitamin B6 and vitamin E, and over 20% had inadequate intakes of thiamin and vitamin B12. When assessed with the MNA-SF tool, 53% were classified as being at risk of malnutrition. When using the MUST screening tool, 39%, were classified as being at risk of malnutrition. Anaemia rates were high in both men and women (57%). Conclusion: We have shown that malnutrition and inadequate micronutrient intakes are prevalent in rest home residents in the lower South Island. More research and strategies are needed to ensure that rest home residents are gaining the appropriate level of nutrition required to stay healthy and functional for as long as possible. 

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  • He kupu tuku iho mo tenei reanga : Te ahua o te tuku korero

    Higgins, Rawinia Ruth (1999)

    Masters thesis
    University of Otago

    170 leaves ; 30 cm. Includes bibliographical references. University of Otago department: Māori, Pacific and Indigenous Studies. "March 1999."

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  • New Zealand’s legal profession – at a cross-roads?

    Leslie, Nicola K (2005)

    Honours Dissertation thesis
    University of Otago

    What do you call 100 lawyers at the bottom of the ocean? 'A good start!' New Zealand's legal profession is an easy scapegoat for public criticism. Yet barristers and solicitors are a tightly regulated profession. This paper aims to understand and analyse the current climate within the legal services market in New Zealand. Why is our legal profession under such attack? It seems ironic that a profession which aspires to high ideals could be the subject of such criticism. Yet we rarely consider why such high standards are demanded of a profession. Chapter One will discuss the concept of a profession, and show whether the legal profession in New Zealand can retain such a position. If there is to be any answer to disparaging remarks about lawyers, we must identify and resolve the criticisms of lawyers in New Zealand. Chapter Two will discuss the criticisms directed at barristers and solicitors, to understand why public confidence in our legal profession may be threatened. Ironically the legal profession is subject to a number of different controls. Parliament, the Courts, the profession's own representative bodies at both a national and local level and individual clients all impact on lawyers' practise. Chapter Three will discuss how each institution has responded to the criticisms made of lawyers. Chapter Four will assess any resulting concerns of the profession which remain problematic. This paper will review the legal profession in New Zealand. For all those who practise as barristers and solicitors this is your collective reputation at risk. It is a review with which all lawyers should be particularly concerned. [Introduction]

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  • The development of Otago's main road network

    Baker, Neill Reginald (1969)

    Masters thesis
    University of Otago

    x, 112 leaves :ill. (some col.), maps ; 30 cm. Includes bibliographical references. University of Otago department: Geography.

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  • Effect of alcohol exposure in early gestation on brain development

    Li, Yuhong (2005)

    Doctoral thesis
    University of Otago

    Fetal alcohol spectrum disorders (FASD), caused by maternal alcohol consumption during pregnancy, has been extensively studied in the human. Animal studies show that alcohol exposure during very early development may result in severe brain damage, often incompatible with a postnatal life. However, for surviving offspring it is unknown whether they suffer long term brain damage. The final assembly of the mature brain results from a controlled balance between proliferation of glial and neuronal precursors and programmed cell death. The overall aim of the current study was to use a physiologically relevant mouse model to assess the acute and long-term effects of binge alcohol exposure on the early embryo, to simulate human pregnancy at the third week of gestation when pregnancy may be undetected. A number of paradigms were used to assess the acute dose-response effect, the blood alcohol concentration (BAC) profile and the extent of cell death following alcohol exposure on gestational day (G) 7.5. The exposure paradigms were single binge IG6.5, IG4.5, IP4.5, or an extended binge IG4.5+, IG3.0+. Two control groups were Con6.5 and Con4.5+. Acute cell death was determined using terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL), activated caspase-3 staining, and transmission electron microscopy. Cell proliferation was investigated using S-phase immuno-labeling, bromodeoxyuridine (BrdU) birthdating and immuno-detection (BrdU/anti-BrdU). The long-term effects were investigated at G18.5 and postnatal day (PN) 60. Unbiased stereological methods were used to assess the effect of ethanol exposure at G7.5 on neocortical volume, cell number and density of neurons, glial cells, and capillary cells at PN60. The first principal finding of the present study was that binge ethanol exposure during gastrulation resulted in acute apoptotic cell death in the ectoderm of the mouse embryo. Cell death was dependent on both peak BAC and the duration of elevated BAC. Significant increased cell death (TUNEL labeling) was observed in groups IG6.5 (9.43 ± 2.08%) and IG4.5+ (8.97 ± 2.12%) compared with control groups Con6.5 (2.14 ± 0.09%) and Con4.5+ (2.81 ± 0.36%). There was no significant increased cell death in ethanol exposed groups IG4.5 (3.43 ± 0.45%), IP4.5 (3.68 ± 0.67%), or IG3.0+ (1.72 ± 0.24%). TEM analysis revealed that cell death exhibited characteristics of the apoptotic pathway. The second principal finding of the present study was that binge ethanol exposure during gastrulation resulted in acute arrested proliferation in the ectoderm of the mouse embryo. The S-phase proliferation was significantly decreased within the whole ectoderm in the ethanol exposed group IG6.5 (45.58 ± 2.34%) compared with control group Con6.5 (62.08 ± 3.11%). The third principal finding of the present study was that binge ethanol exposure during gastrulation induced the long term effect of laminate disorganization in the neocortex. The incidence of abnormal lamination was 87.5% in IG6.5 compared with 16.7% in IG3.0+ and 14.3% in Con6.5. Although ethanol exposure increased embryonic reabsorption, decreased litter size, and increased abnormal offspring, neocortical volume, and the total number of neurons, glial cells, and capillary cells was not affected. The total number (10⁶) of neurons, glial cells, and endothelial cells respectively was 12.221 ± 0.436, 4.865 ± 0.167, and 2.874 ± 0.234 in IG6.5; 11.987 ± 0.416, 4.942 ± 0.133, and 2.922 ± 0.130 in IG3.0+; and 11.806 ± 0.368, 5.166 ± 0.267, and 3.284 ± 0.217 in controls, at PN60. These results provide important information pertinent to fetal outcome for those women who drink heavily in early pregnancy. The results also demonstrate the importance of the pattern of ethanol exposure and blood alcohol concentration in determining the magnitude of ethanol's teratogenic impact. Ethanol exposure on G7.5 that resulted in a high transient BAC, induced disorganized neocortical lamination, indicative of a permanent structural change. This disruption may result in altered neocortical function and requires further investigation.

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  • Synthesis and characterisation of poly(acrylic acid) microspheres containing β-cyclodextrin

    Bibby, David C. (1999)

    Doctoral thesis
    University of Otago

    xviii, 160 leaves :ill. ; 30 cm. Includes bibliographical references. "February 1999"

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  • BECOME SOME BODY: A history of Aerobics, Instruction, and Body Culture at Les Mills World of Fitness from 1980-1992.

    Andrews, Catherine (1995)

    Honours Dissertation thesis
    University of Otago

    xii, 92 leaves : ill. ; 30 cm.

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  • Telling our professional stories

    Alterio, Maxine (1998)

    Masters thesis
    University of Otago

    [6], 138 leaves :ill. ; 30 cm. Includes bibliographical references.

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  • Analysis of fungal inteins

    Bokor, Annika Anna Maria (2010)

    Doctoral thesis
    University of Otago

    xxvi, 298 leaves :col. ill ; 30 cm. Includes bibliographical references. University of Otago department: Biochemistry. "November 1, 2010"

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  • Larval drift and development of amphidromous fishes, particularly the bluegill bully (Gobiomorphus hubbsi)

    Jarvis, Matthew Graham (2015)

    Masters thesis
    University of Otago

    Amphidromy is a distinct life history strategy found in many aquatic organisms, involving a return migration (‘drift’) to a pelagic feeding habitat (usually the sea), undertaken by newly hatched larvae. The freshwater fish faunas of many Indo-Pacific islands are dominated by amphidromous species, yet they remain understudied, especially their larval stages. Amphidromous larvae hatch out exceptionally small and undeveloped, and so face a range of specific challenges during migration such as irreversible starvation and failed development if migration is delayed, as well as management difficulties due to their small size. Basic ecological knowledge such as timing and extent of migration remains unknown, but is crucial to the management of amphidromous species. It was therefore the aim of this thesis to further our knowledge on the larval ecology and migration of a number of New Zealand’s amphidromous fish species. This thesis examines patterns of larval drift and development, focussing on the bluegill bully (Gobiomorphus hubbsi), an endemic eleotrid. A distinct diel and spatial drift pattern was documented, with the vast majority of fish larvae migrating to sea within a few hours of sunset. It is suggested that targeting conservation measures within this window of drift represents a potentially beneficial management strategy for amphidromous species. Development and starvation of larvae was also examined, both through field studies and lab experiments. No distinct pattern of starvation was observed in larvae during their seaward migration, however larvae retained in freshwater failed to develop to as complete a state as those transferred to seawater, implying delayed migration may adversely affect amphidromous fishes developmentally, ultimately reducing their success upon reaching the sea. These results indicate both threats to amphidromous fishes during their larval migration, and a potential approach which may prove beneficial in conserving these fascinating and vulnerable species.

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  • Self-Regulation During A Reading-To-Write Task: A Sociocultural Theory-Based Investigation

    Wall, Bunjong (2015)

    Doctoral thesis
    University of Otago

    Most composition studies focus on students’ writing processes and written products without integrating reading into their research activities. More recently, researchers have acknowledged the reciprocal reading-writing relationship and begun to examine reading-to-write or discourse synthesis processes. Research shows that discourse synthesis is cognitively demanding and that most second language writers lack linguistic, mental, and sociocultural resources to perform this task effectively. Existing studies have not emphasised the role of self-directed speech as a self-regulatory strategy while students read multiple texts in order to write. This thesis addresses this gap in the literature. Informed by sociocultural theoretical notions that cognition is socially mediated and that speech is instrumental in learning and development, this qualitative multiple-case-studies thesis examined how five Thai EFL tertiary students applied their knowledge and skills, following explicit concept-based instruction on discourse synthesis, textual coherence, and argumentation. The researcher designed and delivered a four-week intervention in which the learning concepts, materials, and verbalisation were instrumental in promoting conceptual understanding and reading-to-write performance. Explicitly taught verbalisation or self-directed speech, together with learning materials specifically designed as schemes for task orientation, was a key for self-regulation as participants read multiple texts in order to compose an argument essay. The study adopted an activity theoretical framework and microgenetic analysis. The analysis aimed to describe the participants as social beings and to outline their self-regulation as it unfolded during a mediated reading-to-write activity. Data from a pre-task questionnaire on strategy use and from a post-task written self-reflection form together with video-recorded data during the end-of-intervention discourse synthesis task and interview data were triangulated to examine how reading-to-write activities were mediated and regulated. Findings were organised around four main themes: participants as readers and writers of English, essay argument structure, microgenetic findings of unfolding self-regulatory behaviour during the discourse synthesis activity, and developmental gains as perceived by the participants during concept-based instruction. The findings in this study show that participants’ reading and writing difficulties and argumentation were, in part, shaped by the social, historical and cultural factors in the Thai EFL context, and that participants’ strategic application of verbalisation and learning materials mediated their developmental changes and self-regulation. During the discourse synthesis task, participants used self-directed speech as a strategy and demonstrated varying degrees of self-regulation over various task aspects. Successful task completion indicated purposeful mediated learning with strong orientation towards the task, based on conceptual understanding, specific goals, and voluntary inclusion of learning materials as psychological tools. All participants reportedly viewed verbalisation as a useful strategy and most participants were able to describe their increased theoretical understanding of the concepts explicitly taught. However, their conceptual understanding did not always translate into their actual performance. These findings raise pedagogical implications and highlight the need for human mediators to make explicit the learning concepts, materials and strategies, so that theoretical understanding and learning tools can lead to meaningful task performance. Based on the above findings, this thesis proposes a self-regulation model and calls for future research to investigate how explicit verbalisation training can be systematised.  

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  • Hostility in the House of God: An "Interested" Investigation of the Opponents in 1 and 2 Timothy

    Thornton, Dillon T. (2015)

    Doctoral thesis
    University of Otago

    To my knowledge, Pietersen’s study (2004) is the only monograph published in the last twenty years that has focused on the opponents in the Pastoral Epistles, but his work is not exegetical. In this thesis, I concentrate on 1 and 2 Timothy, the two letters purportedly dispatched to Ephesus. I assemble the relevant pericopae of the letters and offer an exegetical analysis of them, with the intention of providing, first, a composite sketch of the ideology of the opposing group and, second, an in-depth account of the way the faithful Pauline community was to engage these opponents. The first chapter of the thesis is devoted to preliminary issues and methodology. I argue that 1 and 2 Timothy constitute two types of letter, both dispatched in the late first century to the Christian community in Ephesus, each addressing a stage of the conflict in which the community was engaged. I further argue that the polemical portions of the letters reveal specific information about this conflict. I then formulate a stringent method for the study of Paul’s opponents. I summarize and critique historical-critical methodologies and bring the most recent work on theological interpretation of Scripture into dialogue with these methodologies. The result is a new approach to the study of opponents, one that remains rigorously tethered to the primary text and that is characterized by ecclesial concern. In chapters two to six, I apply this method to 1 and 2 Timothy. In chapter two, I offer an exegetical analysis of the explicit units of 1 Timothy, those units where we have clear and certain reference to the opponents (1:3-7, 18-20; 4:1-5; 6:2b-5, 20-21a). Chapters three and four focus on the implicit units in 1 Timothy, those units where we have highly probable reference to the opponents (1:8-11; 2:9-15; 4:6-10; 5:9-16; 6:6-10). In chapter five, I turn to 2 Timothy, analyzing the three explicit units (2:14-26; 3:1-9; 4:1-5) and the one implicit unit of the letter (2:8-13). In chapter six, I bring together the full gamut of data uncovered in the exegetical chapters, offering overall conclusions about the opponents in 1 and 2 Timothy. As a follow-up to this, I enumerate what I perceive to be the most important implications of the findings for the house of God today. My findings may be summarized as follows. I conclude that the opponents came from within the Christian community in Ephesus and that their teaching is best described as an erroneous eschatological position that derived from the complexity of Paul’s views. Each doctrinal and ethical issue raised in the explicit and implicit units of the letters can be explained as a distortion of Pauline doctrine. Additionally, I contend that the opponents had an active “didactic/evangelistic ministry” in Ephesus, for which they received remuneration. They likely set out to recruit as large a following, and as large an income, as possible, but found a particularly fruitful field among the women in Ephesus. As I formulate my view of the opponents, I critique a number of the extant theories, including “Gnostic,” Jewish, and Proto-Montanist identifications. I also conclude that the author engages with the false teachers in significant ways throughout the letters. I draw attention to a number of literary and theological maneuvers that are intended to counteract the opponents’ influence and/or to bolster the faithful community’s confidence as they struggle against the opponents. These include the way the author turns features of the opponents against them, his use of the faithful saying formula, the way he relates the Triune God and the principal adversary, Satan, to the opponents, and the way the author portrays the gospel as an unstoppable force in his own ministry. Though the author pictures the opponents as enemies of God, he also highlights the fact that the opponents are not beyond the reach of God’s grace; thus, Timothy is called to minister the saving word to them. In the explicit and implicit units, the author instructs Timothy to occupy himself with five specific activities: reflection on his commissioning and on the apostolic gospel, rejection of the opponents’ claims, proclamation of the healthy teaching, demonstration of the gospel in actions that are pleasing to God, and correction of the false teachers themselves. The wider faithful community is at least implicitly included in the activities of rejection, demonstration, and correction.

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