277 results for Conference poster

  • Factors Influencing the Aroma Stability of Sauvignon blanc Wines

    Herbst-Johnstone, Mandy; Nicolau, L; Kilmartin, Paul (2010-07)

    Conference poster
    The University of Auckland Library

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  • Role of Antioxidants and Polyphenols in the Stability of Sauvignon Blanc Aromas

    Herbst, M; Kilmartin, PA; Nicolau, L (2006-02)

    Conference poster
    The University of Auckland Library

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  • Impact of grape harvesting on varietal thiols in Sauvignon blanc wines

    Allen, T; Herbst-Johnstone, Mandy; Girault, M; Butler, P; Logan, G; Jouanneau, S; Nicolau, L; Kilmartin, PA (2012-02-03)

    Conference poster
    The University of Auckland Library

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  • A randomized controlled trial of Triple P Online for parents of hyperactive/ inattentive pre-schoolers

    Franke, Nike; Keown, Louise; Sanders, M (2015-03-20)

    Conference poster
    The University of Auckland Library

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  • Data acquisition and integration protocol on the Ahuahu/Great Mercury Island Archaeological Project

    Pillay, P; Barrett, Matthew; Emmitt, Joshua; Mackrell, Timothy; Phillipps, Rebecca (2017-06-22)

    Conference poster
    The University of Auckland Library

    On the Ahuahu/Great Mercury Island Project a wide range of technology is used to record large quantities of data. Laser scanners for generating 3D models of the landscape, GPS for logging points during pedestrian survey, drones capture aerial photography, tablets are used for in-field artefact registry and analysis, and total stations for recording the location of artefacts, features, deposits, and points for Terrain Irregular Networks (TINs). The use of such technology in conjunction with excavation requires a rigid workflow to maximise use of time and maintain recording standards, while minimising data loss and disruption to excavation. This workflow includes the post-field processing of data which are ultimately appended to a master relational database. Following a workflow in this way allows the efficient integration, management, and comparison of data from multiple sites across multiple field seasons.

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  • Recent experiences in using TOUGH2 for geothermal modelling

    Clearwater, Emily; Yeh, Angus; O'Sullivan, John; Kaya, Eylem; Croucher, Adrian; Cui, T; OSullivan, Michael; Zarrouk, Sadiq; Austria, JJC; Ciriaco, Anthony; Archer, Rosalind; Dempsey, David (2012-04-17)

    Conference poster
    The University of Auckland Library

    The geothermal modelling group in Engineering Science (University of Auckland) is involved with several geothermal R&D projects. On the development side we are running models of Ohaaki, Wairakei, Ngawha, Reporoa, Wayang Windu and Lihir. Our experiences in these projects have led on to several parallel research projects. Our model of Wairakei-Tauhara is so large that it also contains the Rotokawa system and the edge of the Ngatamriki system. Trying to understand the large-scale convection process at Wairakei-Tauhara has led on to studies of more generic convection studies and studies of larger areas of the TVZ. It has also led on to deeper models which require equations of state that can handle high pressures and temperatures. We have developed one for pure water but now wish to extend it to include CO2 and NaCl. With larger and larger models the computational demand increases quickly and we are now routinely using TOUGH_MP, the parallel version of TOUGH2. Also with large complex models dealing with input and output is a major task and we have developed a suite of PYTHON scripts (called pyTOUGH) for carrying out several model management tasks. One of the biggest challenges in geothermal modelling is model calibration and we have carried out studies using inverse modelling with iTOUGH and PEST and also Markov Chain Monte Carlo methods (MCMC). We are also carrying out miscellaneous studies of resewrvoir physics several of which involve fluid/rock interaction, for example the effects of cold water injection on permeability and subsidence in geothermal fields.

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  • Coronary artery bifurcation haemodynamics - comparison between phase contrast MRI and computational fluid dynamics

    Beier, Susann; Ormiston, J; Webster, M; Cater, John; Medrano-Garcia, P; Young, Alistair; Cowan, Brett (2014-01-17)

    Conference poster
    The University of Auckland Library

    Coronary atherosclerosis is common at vessel bifurcations. A quantitative approach to measuring blood velocity, vorticity and more complex flow features at bifurcations would enhance the understanding of the mechanisms of atheroma development, and potentially predict vessels at highest risk. The aim of this work was to validate 4D phase contrast (PC) magnetic resonance imaging flow measurements using a simplified arterial model of the left main coronary bifurcation against computational fluid dynamic (CFD) modelling.

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  • Quality of Life in Fit Elderly Patients with Chronic Lymphocytic Leukemia (CLL) Receiving Oral Fludarabine-Based Regimens As First Line Therapy: Australasian Leukaemia and Lymphoma Group (ALLG) CLL5 Trial

    Suneet, S; Gill, D; Turner, PD; Renwick, WEP; Latimer, M; Mackinlay, N; Berkahn, Leanne; Simpson, DR; Campbell, P; Forsyth, C; Cull, G; Harrup, R; Best, G; Bressel, M; Di Iulio, J; Kuss, BJ; Mulligan, S (2015-12-03)

    Conference poster
    The University of Auckland Library

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  • C/EBP?? Expression in Primary Human Glial Cells

    Rustenhoven, Justin; Smith, AM; Park, In; Jansson, D; Dragunow, Michael (2013-08-26)

    Conference poster
    The University of Auckland Library

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  • Phagocytosis by human brain pericytes: implications for Alzheimer???s disease

    Rustenhoven, Justin; Scotter, Emma; Smyth, L; Park, In; Curtis, Maurice; Faull, Richard; Graham, S; Dragunow, Michael (2016-06-15)

    Conference poster
    The University of Auckland Library

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  • Kai Time in ECE Survey

    Gerritsen, Sarah; Morton, Susan; Wall, C (2014-06-11)

    Conference poster
    The University of Auckland Library

    Kai Time in ECE is a one-off online survey collecting information about nutrition and physical activity practices and policies for 3-4 year olds in licensed Early Childhood Education (ECE) services in Auckland, Counties Manukau and Waikato. The survey results will be used in PhD research on the influence of childcare on preschool dietary patterns and body size.

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  • Modelling of Gas Hydrate Dissociation During The Glacial-Inter-glacial Cycles, Case Study The Chatham Rise, New Zealand

    Oluwunmi, Paul; Pecher, Ingo; Archer, Rosalind; Moridis, GJ; Reagan, MT (2015-12-15)

    Conference poster
    The University of Auckland Library

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  • Arabic emphatics are uvularized

    Al-Tairi, Hamed; Brown, Jason; Watson, Catherine; Gick, B (2016-10-21)

    Conference poster
    The University of Auckland Library

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  • Structure-based design of small molecule modulators of the adrenomedullin 1 receptor

    Liew, Lydia; Burns, Erica; Jamaluddin, Muhammad; Bonnet, Muriel; Flanagan, JU; Hay, Deborah; Hay, Michael (2015-09-21)

    Conference poster
    The University of Auckland Library

    Adrenomedullin (AM) is peptide hormone which is an avid promoter of angiogenesis in a variety of models and is upregulated by hypoxia through a HIF-1a response element on the AM gene. AM administration to adult mice increases the number of blood and lymphatic vessels at the site of an injury. AM can act upon endothelial cells derived from both blood and lymphatic vessels to promote neovascularisation, proliferation and migration. Consequently, there is considerable interest in modulating this important angiogenic pathway. Although a truncated peptide antagonist (AM22-52) is reported to reduce tumour growth and vascularization, currently, there are no small molecules known to interact with AM receptors. Antagonists of AM signalling would have potential as anti-angiogenesis agents for cancer therapy, while agonists would have applications in wound healing and lymphedema settings. Many effects of AM are mediated through the AM1 receptor, which consists of two subunits: the calcitonin receptor-like receptor (CLR) (a G protein-coupled receptor) and receptor activity-modifying protein (RAMP2). A closely related peptide, calcitonin gene-related peptide (CGRP), has a similar receptor; the CGRP receptor, which is composed of CLR with RAMP1. Extensive drug discovery efforts have produced a family of CGRP receptor antagonists (e.g., telcagepant, olcegepant) with clinical activity against migraine. X-ray crystal structures of the RAMP1/CLR extra-cellular domain (ECD) complex showed that these antagonists occupy a binding site at the CLR and RAMP1 interface, and so block CGRP binding. A recent crystal structure of the AM1 receptor ECD complex with an AM peptide fragment bound revealed a distinct ligand binding groove that provides new insights for the discovery of AM1 receptor selective molecules. We have used these crystal structures to design small molecules that anchor to backbone residues in the CLR subunit (THR122) and extend into the binding groove of the AM1 receptor, mimicking the interactions of the antagonist telcagepant at the CGRP receptor. A benzimidazolone motif, known to bind THR122 of the CLR subunit, was linked to a variety of units in an effort to impart selectivity towards the AM1 receptor. Activity at the AM1 and CGRP receptors was evaluated using a combination of cAMP and ??-arrestin recruitment assays. All compounds were independently screened (at least n=2) in the absence and presence of AM or CGRP to check for modulator activity or peptide-independent activity. We have identified a series of AM1 receptor selective small molecules which appear to act as positive allosteric modulators of AM activity, rather than antagonists. We report our exploration of this class of AM1 modulators, which represent first-in-class molecules.

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  • What???s on the INSIDE matters - exploring and characterising the 'Thin on the Outside Fat on the Inside' profile across ethnicities: the TOFI_Asia study

    Sequeira, Ivana; Yip, Wilson; Lu, Louise; Poppitt, Sally (2016-10-20)

    Conference poster
    The University of Auckland Library

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  • Critical transitions in the public space of contemporary Chinese cities: Evaluating the ???otherness??? of the malls of consumption and spectacle in Changsha

    Manfredini, Manfredo; Xin, T; Wei, C (2015)

    Conference poster
    The University of Auckland Library

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  • Explaining parallel computing to your grandmother: Drive-by learning for developing soft skills by communicating with a general audience

    Varoy, E; Aziz, M; Burrows, J; Sinnen, Oliver; Giacaman, Nasser (2016-05-23)

    Conference poster
    The University of Auckland Library

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