25,059 results for Journal article

  • The future of student self-assessment: A review of known unknowns and potential directions

    Panadero, E; Brown, Gavin; Strijbos, JW (2016-12)

    Journal article
    The University of Auckland Library

    This paper reviews current known issues in student self-assessment (SSA) and identifies five topics that need further research: (1) SSA typologies, (2) accuracy, (3) role of expertise, (4) SSA and teacher/curricular expectations, and (5) effects of SSA for different students. Five SSA typologies were identified showing that there are different conceptions on the SSA components but the field still uses SSA quite uniformly. A significant amount of research has been devoted to SSA accuracy, and there is a great deal we know about it. Factors that influence accuracy and implications for teaching are examined, with consideration that students??? expertise on the task at hand might be an important prerequisite for accurate self-assessment. Additionally, the idea that SSA should also consider the students??? expectations about their learning is reflected upon. Finally, we explored how SSA works for different types of students and the challenges of helping lower performers. This paper sheds light on SSA research needs to address the known unknowns in this field.

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  • Factors associated with change in radiographic damage scores in gout: a prospective observational study

    Eason, A; House, ME; Vincent, Zoe; Knight, J; Tan, P; Horne, Anne; Gamble, Gregory; Doyle, Anthony; Taylor, WJ; Dalbeth, Nicola (2016-12)

    Journal article
    The University of Auckland Library

    Radiographic damage is frequently observed in patients with longstanding gout. The aim of this prospective observational study was to determine factors associated with change in radiographic damage scores in gout.People with gout and disease duration <0.001).Development of new subcutaneous tophi and baseline radiographic damage are associated with progressive joint damage scores in people with gout. These data provide further evidence that the tophus plays a central role in bone erosion in gout.

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  • Efficient experimental characterisation of the permeability of fibrous textiles

    Swery, Elinor; Allen, Thomas; Comas-Cardona, S; Govignon, Q; Hickey, C; Timms, J; Tournier, L; Walbran, A; Kelly, Piaras; Bickerton, Simon (2016-12)

    Journal article
    The University of Auckland Library

    Two experimental set-ups used to characterise the in-plane and through-thickness permeabilities of reinforcing textiles have been developed and are presented. Both the experimental testing and data processing techniques used have been selected to ensure that the characterisation is completed in an efficient and robust method, increasing the repeatability of tests while minimising user induced errors as well as the time and resources needed. A number of key results and outputs obtained are presented from tests carried out on a plain woven reinforcing textile with a range of number of layers and at different fibre volume fractions.

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  • Relations between teachers' achievement, over- and underestimation, and students' beliefs for M??ori and P??keh?? students

    Davies, Christine; Peterson, Elizabeth (2016-10)

    Journal article
    The University of Auckland Library

    In the New Zealand context, the indigenous M??ori group achieve below their P??keh?? (European) peers in most academic subjects. The gap begins early in elementary school and is evident throughout schooling. Historically, this has been of concern to researchers, educators, and policy makers because M??ori are disadvantaged socially and economically. Teacher expectations are known to contribute to student achievement and, similarly, some student beliefs have been associated with achievement. The current study explored student beliefs and teacher expectations in relation to M??ori (n???=???127) and P??keh?? (n???=???523) middle school students, aged 10???14 years. Teachers were more likely to underestimate M??ori and overestimate P??keh?? students although this difference disappeared when school socioeconomic status was controlled. M??ori students more strongly endorsed performance goals than P??keh??. Greater achievement gains over one year were found in schools in high socioeconomic areas. For M??ori students, beginning-of-year achievement, school socioeconomic status, holding a performance orientation, and having low levels of peer support predicted their gains whereas for P??keh?? students, only prior achievement, school socioeconomic status and being male were associated with higher end-of-year achievement. The findings are discussed in relation to the implications for M??ori and P??keh?? students and their schooling. The inclusion of a culturally-based intervention which focuses on improving student???teacher relationships, raising teacher efficacy for teaching M??ori, and including culturally appropriate teaching methods is recommended, particularly for teachers teaching in low socioeconomic schools. Such interventions may help to increase M??ori achievement and decrease the ethnic achievement gap.

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  • The physiological optics of the lens

    Donaldson, Paul; Grey, Angus; Heilman, Bianca; Lim, Julie; Vaghefi Rezaei, Seyed (2017-01)

    Journal article
    The University of Auckland Library

    Abstract The optical properties of the ocular lens are important to overall vision quality. As a transparent biological tissue, the lens contributes to the overall and dynamic focussing power of the eye, and corrects for optical errors introduced by the cornea. The optical properties of the lens change throughout life. Alterations to the refractive properties and transparency of the lens result in presbyopia and cataract, respectively. However, it is not well understood how changes to lens cellular structure and function initiate these changes in refraction and transparency. Here, we attempt to bridge this knowledge gap by reviewing how the optical properties of the lens are first established, and then maintained at the cellular level throughout the lifetime of an individual. Central to this understanding is the fact that the lens has a microcirculation system that generates a flux of ions and water that circulates through the lens. By supporting ionic and metabolic homeostasis in the lens, the system actively maintains lens transparency, and by regulating the steady state water content of the lens, controls the two key parameters, lens geometry and the gradient of refractive index, which determine the refractive properties of the lens. Thus, water transport is emerging as the critical parameter that links the transparency and refractive properties of the lens at the cellular level, and highlights the need to study how age-related changes in water transport result in presbyopia and cataract, the leading causes of refractive error and blindness in the world today.

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  • Monitoring the depth of anesthesia using entropy features and an artificial neural network

    Shalbaf, R; Behnam, H; Sleigh, James; Steyn-Ross, A; Voss, LJ (2013-08-15)

    Journal article
    The University of Auckland Library

    Monitoring the depth of anesthesia using an electroencephalogram (EEG) is a major ongoing challenge for anesthetists. The EEG is a recording of brain electrical activity, and it contains valuable information related to the different physiological states of the brain. This study proposes a novel automated method consisting of two steps for assessing anesthesia depth. Initially, the sample entropy and permutation entropy features were extracted from the EEG signal. Because EEG-derived parameters represent different aspects of the EEG features, it would be reasonable to use multiple parameters to assess the effect of the anesthetic. The sample entropy and permutation entropy features quantified the amount of complexity or irregularity in the EEG data and were conceptually simple, computationally efficient and artifact-resistant. Next, the extracted features were used as input for an artificial neural network, which was a data processing system based on the structure of a biological nervous system. The experimental results indicated that an overall accuracy of 88% could be obtained during sevoflurane anesthesia in 17 patients to classify the EEG data into awake, light, general and deep anesthetized states. In addition, this method yielded a classification accuracy of 92.4% to distinguish between awake and general anesthesia in an independent database of propofol and desflurane anesthesia in 129 patients. Considering the high accuracy of this method, a new EEG monitoring system could be developed to assist the anesthesiologist in estimating the depth of anesthesia in a rapid and accurate manner.

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  • Are more trials of calcium supplements really needed?

    Bolland, Mark; Grey, Andrew; Reid, Ian (2017-09)

    Journal article
    The University of Auckland Library

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  • Proteolytic activity during cortical development is distinct from that involved in hypoxic ischemic injury

    Ranasinghe, Himani; Williams, CE; Christophidis, Larissa; Mitchell, Murray; Fraser, Mhoyra; Scheepens, Arjan (2009)

    Journal article
    The University of Auckland Library

    Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases involved in brain development and the etiology of adult cerebral injuries. In this study, we determined the MMP-2 and 9 responses following hypoxic ischemia (HI) injury in the developing brain. First, we characterized the developmental changes of MMP activity in the rat brain from embryonic day 18 (E18) to postnatal day 120 (P120). MMP-2 activity was high from E18 to P3 and decreased with age (P???0.001), while MMP-9 activity was not detectable. MMP-2 immunoreactivity was closely associated with differentiating cortical plate and subplate neurons. Next, we characterized the proteolytic changes after unilateral HI brain injury in 3- (P3) and 21- (P21) day-old rats. Zymography revealed that in the P21 rat brain, MMP-9 activity (150 and 92 kDa forms) was increased at 6 h and remained elevated 24 h post-injury in the ipsilateral injured hemisphere (P???0.001), whereas there was a gradual increase in MMP-2 (65 kDa) activity, reaching a peak at 5 days (P???0.001). Similarly, quantitative real time polymerase chain reaction (qRT-PCR) indicated significant elevations in MMP-9 and MMP-2 mRNA expression in the injured cortex (P???0.05) and hippocampus (P???0.05) at 1 and 5 days post-injury, respectively in the P21 rat brain. In the P3 rat brain, zymography results revealed that both pro (92 kDa) and cleaved (87 kDa) MMP-9 activities were upregulated in the ipsilateral injured hemisphere from 6 h to 1 day after injury (P???0.001). In contrast, cleaved MMP-2 (60 kDa) was only moderately upregulated at 6 h (P???0.01), while pro MMP-2 (65 kDa) levels were unaffected. MMP-9 mRNA expression was also increased at 6 h (P???0.05) following injury at P3, whereas MMP-2 expression remained unchanged compared with the uninjured contralateral hemisphere. Immunohistochemistry indicated that MMP-9 protein expression was localized predominantly to neurons and peri-vascular astrocytes in the affected regions at early time points, whereas MMP-2 was present on reactive astrocytes surrounding the infarct at later time points. Together, these results indicate that MMP-2 may be primarily associated with the development and differentiation of cortical plate neurons and wound recovery processes. Conversely, MMP-9 appeared to be associated with more acute processes during the period of lesion development.

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  • The Virtual Supermarket: An Innovative Research Tool to Study Consumer Food Purchasing Behaviour

    Waterlander, Willemina; Scarpa, M; Lentz, D; Steenhuis, IHM (2011)

    Journal article
    The University of Auckland Library

    Background: Economic interventions in the food environment are expected to effectively promote healthier food choices. However, before introducing them on a large scale, it is important to gain insight into the effectiveness of economic interventions and peoples??? genuine reactions to price changes. Nonetheless, because of complex implementation issues, studies on price interventions are virtually non-existent. This is especially true for experiments undertaken in a retail setting. We have developed a research tool to study the effects of retail price interventions in a virtual-reality setting: the Virtual Supermarket. This paper aims to inform researchers about the features and utilization of this new software application. Results: The Virtual Supermarket is a Dutch-developed three-dimensional software application in which study participants can shop in a manner comparable to a real supermarket. The tool can be used to study several food pricing and labelling strategies. The application base can be used to build future extensions and could be translated into, for example, an English-language version. The Virtual Supermarket contains a front-end which is seen by the participants, and a back-end that enables researchers to easily manipulate research conditions. The application keeps track of time spent shopping, number of products purchased, shopping budget, total expenditures and answers on configurable questionnaires. All data is digitally stored and automatically sent to a web server. A pilot study among Dutch consumers (n=66) revealed that the application accurately collected and stored all data. Results from participant feedback revealed that 83% of the respondents considered the Virtual Supermarket easy to understand and 79% found that their virtual grocery purchases resembled their regular groceries. Conclusions: The Virtual Supermarket is an innovative research tool with a great potential to assist in gaining insight into food purchasing behaviour. The application can be obtained via an URL and is freely available for academic use. The unique features of the tool include the fact that it enables researchers to easily modify research conditions and in this way study different types of interventions in a retail environment without a complex implementation process. Finally, it also maintains researcher independence and avoids conflicts of interest that may arise from industry collaboration.

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  • Expert views on most suitable monetary incentives on food to stimulate healthy eating

    Waterlander, Willemina; Steenhuis, IHM; De Vet, E; Schuit, AJ; Seidell, JC (2010)

    Journal article
    The University of Auckland Library

    Background: Pricing strategies are an important component in the marketing mix and may also be useful in stimulating healthier food choices. However, due to competing interests and feasibility problems, the introduction of pricing strategies is complicated. For successful introducing food pricing strategies, it is essential to explore incentives that are not only promising but also realisable and being approved by different sectors. Methods: We aimed to assemble a list of pricing strategies by exploring expert views using the Delphi method. Subjects included experts from academia, industry, retail, agriculture, policymakers, consumers and non-governmental organizations. Data were collected in three rounds. In round one, experts designed promising pricing strategies. Based on a time-budget model incorporating Sleep, Leisure, Occupation, Transportation, and Home-based activities (SLOTH) these strategies were in the subsequent rounds judged on several criteria. Results were analysed using median and inter quartile deviations (IQD) scores. Results: We found fair consensus levels among experts and a varied list of promising pricing strategies. The panel agreed on the potential success of offering small presents, providing price-cuts on healthy foods, and discounting healthier foods more frequently. Also, it was found that experts gave higher rates to pricing strategies for which the implementation responsibilities could be placed elsewhere. Conclusion: The resulted list of promising monetary incentives is an essential first step for the future design of pricing strategies. Following this study, it is important to determine how to make solid agreements on responsibility and implementation issues. Also, consumer perceptions regarding the proposed pricing strategies should be studied.

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  • Exclusion of known corneal dystrophy genes in an autosomal dominant pedigree of a unique anterior membrane corneal dystrophy

    Vincent, Andrea; Markie, D; De Karolyi, B; Patel, Dipika; Wheeldon, CE; Grupcheva, CN; McGhee, Charles (2009)

    Journal article
    The University of Auckland Library

    Purpose: With advances in phenotyping tools and availability of molecular characterization, an increasing number of phenotypically and genotypically diverse inherited corneal dystrophies are described. We aimed to determine the underlying causative genetic mechanism in a three-generation pedigree affected with a unique anterior membrane corneal dystrophy characterized by early onset recurrent corneal erosions, small discrete focal opacities at the level of Bowman layer and anterior stroma, anterior stromal flecks, and prominent corneal nerves. Methods: Twenty affected and unaffected members of a three-generation family were examined and extensively clinically characterized including corneal topography and in vivo confocal microscopy, and biological specimens were collected for DNA extraction. Mutational analysis of two corneal genes (TGFBI [Transforming Growth factor-beta induced] and ZEB1 [zinc finger E box-binding homeobox 1]) was undertaken, in addition to testing with the Asper Corneal Dystrophy gene chip (Asper Ophthalmics, Tartu, Estonia). Subsequent Genotyping To 11 Known Corneal Gene Loci (COL8A2 [Collagen, Type VIII, Alpha-2], TACSTD2 [Tumor-Associated Calcium Signal Transducer 2], PIP5K3 [Phosphatidylinositol-3-Phosphate 5-Kinase, Type III], GSN [Gelsolin], KERA [Keratocan], VSX1 [Visual System Homeobox Gene 1], COL6A1 [Collagen, Type VI, Alpha-1], MMP9 [Matrix Metalloproteinase 9], KRT3 [Keratin 3]), and two putative loci, 3p14-q13 and 15q22.33???24) was undertaken using polymorphic markers, and haplotypes constructed. Multipoint linkage analysis was performed to generate LOD scores and produce LOD plots across the candidate intervals. Results: No pathogenic sequence variations were detected in TGFBI or ZEB1 of the proband nor on the Asper Corneal Dystrophy gene chip (302 mutations in 12 genes). Multipoint linkage analysis of 11 known corneal genes and loci generated negative LOD plots and was able to exclude all genes tested including PIP5K3. Conclusions: Exclusion of linkage to candidate corneal loci combined with an absence of pathogenic mutations in known corneal genes in this pedigree suggest a different genetic causative mechanism in this dystrophy than the previously documented corneal genes. This unique phenotype of an anterior membrane dystrophy may therefore provide an opportunity to identify a new gene responsible for corneal disease.

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  • Monosodium urate monohydrate crystals inhibit osteoblast viability and function: Implications for development of bone erosion in gout

    Chhana, Ashika; Callon, Karen; Pool, Bregtina; Naot, D; Watson, M; Gamble, Gregory; McQueen, Fiona; Cornish, Jillian; Dalbeth, Nicola (2011)

    Journal article
    The University of Auckland Library

    Background Bone erosion is a common manifestation of chronic tophaceous gout. Objectives To investigate the effects of monosodium urate monohydrate (MSU) crystals on osteoblast viability and function. Methods The MTT assay and ??? ow cytometry were used to assess osteoblast cell viability in the MC3T3-E1 and ST2 osteoblast-like cell lines, and primary rat and primary human osteoblasts cultured with MSU crystals. Quantitative real-time PCR and von Kossa stained mineralised bone formation assays were used to assess the effects of MSU crystals on osteoblast differentiation using MC3T3-E1 cells. The numbers of osteoblasts and bone lining cells were quanti??? ed in bone samples from patients with gout. Results MSU crystals rapidly reduced viability in all cell types in a dose-dependent manner. The inhibitory effect on cell viability was independent of crystal phagocytosis and was not in??? uenced by differing crystal length or addition of serum. Long-term culture of MC3T3-E1 cells with MSU crystals showed a reduction in mineralisation and decreased mRNA expression of genes related to osteoblast differentiation such as Runx2 , Sp7 (osterix), Ibsp (bone sialoprotein), and Bglap (osteocalcin). Fewer osteoblast and lining cells were present on bone directly adjacent to gouty tophus than bone unaffected by tophus in patients with gout. Conclusions MSU crystals have profound inhibitory effects on osteoblast viability and differentiation. These data suggest that bone erosion in gout occurs at the tophus???bone interface through alteration of physiological bone turnover, with both excessive osteoclast formation, and reduced osteoblast differentiation from mesenchymal stem cells.

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  • Commissioning and performance of the CMS silicon strip tracker with cosmic ray muons

    Chatrchyan, S; Khachatryan, V; Sirunyan, AM; Adam, W; Arnold, B; Bergauer, H; Bergauer, T; Dragicevic, M; Eichberger, M; Eroe, J; Friedl, M; Fruehwirth, R; Ghete, VM; Hammer, J; Haensel, S; Hoch, M; Hoermann, N; Hrubec, J; Jeitler, M; Kasieczka, G; Kastner, K; Krammer, M; Liko, D; de Abril, I Magrans; Mikulec, I; Mittermayr, F; Neuherz, B; Oberegger, M; Padrta, M; Pernicka, M; Rohringer, H; Schmid, S; Schoefbeck, R; Schreiner, T; Stark, R; Steininger, H; Strauss, J; Taurok, A; Teischinger, F; Themel, T; Uhl, D; Wagner, P; Waltenberger, W; Walzel, G; Widl, E; Wulz, C-E; Chekhovsky, V; Dvornikov, O; Emeliantchik, I; Litomin, A; Makarenko, V; Marfin, I; Mossolov, V; Shumeiko, N; Solin, A; Stefanovitch, R; Gonzalez, J Suarez; Tikhonov, A; Fedorov, A; Karneyeu, A; Korzhik, M; Panov, V; Zuyeuski, R; Kuchinsky, P; Beaumont, W; Benucci, L; Cardaci, M; De Wolf, EA; Delmeire, E; Druzhkin, D; Hashemi, M; Janssen, X; Maes, T; Mucibello, L; Ochesanu, S; Rougny, R; Selvaggi, M; Van Haevermaet, H; Van Mechelen, P; Van Remortel, N; Adler, V; Beauceron, S; Blyweert, S; D'Hondt, J; De Weirdt, S; Devroede, O; Heyninck, J; Kalogeropoulos, A; Maes, J; Maes, M; Mozer, MU; Tavernier, S; Van Doninck, W; Van Mulders, P; Villella, I; Bouhali, O; Chabert, EC; Charaf, O; Clerbaux, B; De Lentdecker, G; Dero, V; Elgammal, S; Gay, APR; Hammad, GH; Marage, PE; Rugovac, S; Velde, C Vander; Vanlaer, P; Wickens, J; Grunewald, M; Klein, B; Marinov, A; Ryckbosch, D; Thyssen, F; Tytgat, M; Vanelderen, L; Verwilligen, P; Basegmez, S; Bruno, G; Caudron, J; Delaere, C; Demin, P; Favart, D; Giammanco, A; Gregoire, G; Lemaitre, V; Militaru, O; Ovyn, S; Piotrzkowski, K; Quertenmont, L; Schul, N; Beliy, N; Daubie, E; Alves, GA; Pol, ME; Souza, MHG; Carvalho, W; Damiao, D De Jesus; Martins, C De Oliveira; De Souza, S Fonseca; Mundim, L; Oguri, V; Santoro, A; Silva Do Amaral, SM; Sznajder, A; Fernandez Perez Tomei, TR; Ferreira Dias, MA; Gregores, EM; Novaes, SF; Abadjiev, K; Anguelov, T; Damgov, J; Darmenov, N; Dimitrov, L; Genchev, V; Iaydjiev, P; Piperov, S; Stoykova, S; Sultanov, G; Trayanov, R; Vankov, I; Dimitrov, A; Dyulendarova, M; Kozhuharov, V; Litov, L; Marinova, E; Mateev, M; Pavlov, B; Petkov, P; Toteva, Z; Chen, GM; Chen, HS; Guan, W; Jiang, CH; Liang, D; Liu, B; Meng, X; Tao, J; Wang, J; Wang, Z; Xue, Z; Zhang, Z; Ban, Y; Cai, J; Ge, Y; Guo, S; Hu, Z; Mao, Y; Qian, SJ; Teng, H; Zhu, B; Avila, C; Baquero Ruiz, M; Carrillo Montoya, CA; Gomez, A; Gomez Moreno, B; Ocampo Rios, AA; Osorio Oliveros, AF; Reyes Romero, D; Sanabria, JC; Godinovic, N; Lelas, K; Plestina, R; Polic, D; Puljak, I; Antunovic, Z; Dzelalija, M; Brigljevic, V; Duric, S; Kadija, K; Morovic, S; Fereos, R; Galanti, M; Mousa, J; Papadakis, A; Ptochos, F; Razis, PA; Tsiakkouri, D; Zinonos, Z; Hektor, A; Kadastik, M; Kannike, K; Muentel, M; Raidal, M; Rebane, L; Anttila, E; Czellar, S; Harkonen, J; Heikkinen, A; Karimaki, V; Kinnunen, R; Klem, J; Kortelainen, MJ; Lampen, T; Lassila-Perini, K; Lehti, S; Linden, T; Luukka, P; Maenpaa, T; Nysten, J; Tuominen, E; Tuominiemi, J; Ungaro, D; Wendland, L; Banzuzi, K; Korpela, A; Tuuva, T; Nedelec, P; Sillou, D; Besancon, M; Chipaux, R; Dejardin, M; Denegri, D; Descamps, J; Fabbro, B; Faure, JL; Ferri, F; Ganjour, S; Gentit, FX; Givernaud, A; Gras, P; de Monchenault, G Hamel; Jarry, P; Lemaire, MC; Locci, E; Malcles, J; Marionneau, M; Millischer, L; Rander, J; Rosowsky, A; Rousseau, D; Titov, M; Verrecchia, P; Baffioni, S; Bianchini, L; Bluj, M; Busson, P; Charlot, C; Dobrzynski, L; de Cassagnac, R Granier; Haguenauer, M; Mine, P; Paganini, P; Sirois, Y; Thiebaux, C; Zabi, A; Agram, J-L; Besson, A; Bloch, D; Bodin, D; Brom, J-M; Conte, E; Drouhin, F; Fontaine, J-C; Gele, D; Goerlach, U; Gross, L; Juillot, P; Le Bihan, A-C; Patois, Y; Speck, J; Van Hove, P; Baty, C; Bedjidian, M; Blaha, J; Boudoul, G; Brun, H; Chanon, N; Chierici, R; Contardo, D; Depasse, P; Dupasquier, T; El Mamouni, H; Fassi, F; Fay, J; Gascon, S; Ille, B; Kurca, T; Le Grand, T; Lethuillier, M; Lumb, N; Mirabito, L; Perries, S; Donckt, M Vander; Verdier, P; Djaoshvili, N; Roinishvili, N; Roinishvili, V; Amaglobeli, N; Adolphi, R; Anagnostou, G; Brauer, R; Braunschweig, W; Edelhoff, M; Esser, H; Feld, L; Karpinski, W; Khomich, A; Klein, K; Mohr, N; Ostaptchouk, A; Pandoulas, D; Pierschel, G; Raupach, F; Schael, S; von Dratzig, A Schultz; Schwering, G; Sprenger, D; Thomas, M; Weber, M; Wittmer, B; Wlochal, M; Actis, O; Altenhoefer, G; Bender, W; Biallass, P; Erdmann, M; Fetchenhauer, G; Frangenheim, J; Hebbeker, T; Hilgers, G; Hinzmann, A; Hoepfner, K; Hof, C; Kirsch, M; Klimkovich, T; Kreuzer, P; Lanske, D; Merschmeyer, M; Meyer, A; Philipps, B; Pieta, H; Reithler, H; Schmitz, SA; Sonnenschein, L; Sowa, M; Steggemann, J; Szczesny, H; Teyssier, D; Zeidler, C; Bontenackels, M; Davids, M; Duda, M; Fluegge, G; Geenen, H; Giffels, M; Ahmad, W Haj; Hermanns, T; Heydhausen, D; Kalinin, S; Kress, T; Linn, A; Nowack, A; Perchalla, L; Poettgens, M; Pooth, O; Sauerland, P; Stahl, A; Tornier, D; Zoeller, MH; Martin, M Aldaya; Behrens, U; Borras, K; Campbell, A; Castro, E; Dammann, D; Eckerlin, G; Flossdorf, A; Flucke, G; Geiser, A; Hatton, D; Hauk, J; Jung, H; Kasemann, M; Katkov, I; Kleinwort, C; Kluge, H; Knutsson, A; Kuznetsova, E; Lange, W; Lohmann, W; Mankel, R; Marienfeld, M; Meyer, AB; Miglioranzi, S; Mnich, J; Ohlerich, M; Olzem, J; Parenti, A; Rosemann, C; Schmidt, R; Schoerner-Sadenius, T; Volyanskyy, D; Wissing, C; Zeuner, WD; Autermann, C; Bechtel, F; Draeger, J; Eckstein, D; Gebbert, U; Kaschube, K; Kaussen, G; Klanner, R; Mura, B; Naumann-Emme, S; Nowak, F; Pein, U; Sander, C; Schleper, P; Schum, T; Stadie, H; Steinbrueck, G; Thomsen, J; Wolf, R; Bauer, J; Bluem, P; Buege, V; Cakir, A; Chwalek, T; De Boer, W; Dierlamm, A; Dirkes, G; Feindt, M; Felzmann, U; Frey, M; Furgeri, A; Gruschke, J; Hackstein, C; Hartmann, F; Heier, S; Heinrich, M; Held, H; Hirschbuehl, D; Hoffmann, KH; Honc, S; Jung, C; Kuhr, T; Liamsuwan, T; Martschei, D; Mueller, S; Mueller, Th; Neuland, MB; Niegel, M; Oberst, O; Oehler, A; Ott, J; Peiffer, T; Piparo, D; Quast, G; Rabbertz, K; Ratnikov, F; Ratnikova, N; Renz, M; Saout, C; Sartisohn, G; Scheurer, A; Schieferdecker, P; Schilling, F-P; Schott, G; Simonis, HJ; Stober, FM; Sturm, P; Troendle, D; Trunov, A; Wagner, W; Wagner-Kuhr, J; Zeise, M; Zhukov, V; Ziebarth, EB; Daskalakis, G; Geralis, T; Karafasoulis, K; Kyriakis, A; Loukas, D; Markou, A; Markou, C; Mavrommatis, C; Petrakou, E; Zachariadou, A; Gouskos, L; Katsas, P; Panagiotou, A; Evangelou, I; Kokkas, P; Manthos, N; Papadopoulos, I; Patras, V; Triantis, FA; Bencze, G; Boldizsar, L; Debreczeni, G; Hajdu, C; Hernath, S; Hidas, P; Horvath, D; Krajczar, K; Laszlo, A; Patay, G; Sikler, F; Toth, N; Vesztergombi, G; Beni, N; Christian, G; Imrek, J; Molnar, J; Novak, D; Palinkas, J; Szekely, G; Szillasi, Z; Tokesi, K; Veszpremi, V; Kapusi, A; Marian, G; Raics, P; Szabo, Z; Trocsanyi, ZL; Ujvari, B; Zilizi, G; Bansal, S; Bawa, HS; Beri, SB; Bhatnagar, V; Jindal, M; Kaur, M; Kaur, R; Kohli, JM; 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Hall-Wilton, R; Jaworski, M; Klabbers, P; Klukas, J; Lanaro, A; Lazaridis, C; Leonard, J; Loveless, R; de Abril, M Magrans; Mohapatra, A; Ott, G; Polese, G; Reeder, D; Savin, A; Smith, WH; Sourkov, A; Swanson, J; Weinberg, M; Wenman, D; Wensveen, M; White, A (2010-03-01)

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    The University of Auckland Library

    During autumn 2008, the Silicon Strip Tracker was operated with the full CMS experiment in a comprehensive test, in the presence of the 3.8 T magnetic field produced by the CMS superconducting solenoid. Cosmic ray muons were detected in the muon chambers and used to trigger the readout of all CMS sub-detectors. About 15 million events with a muon in the tracker were collected. The efficiency of hit and track reconstruction were measured to be higher than 99% and consistent with expectations from Monte Carlo simulation. This article details the commissioning and performance of the Silicon Strip Tracker with cosmic ray muons.

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  • Search for resonances in the dijet mass spectrum from 7 TeV pp collisions at CMS

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    Journal article
    The University of Auckland Library

    A search for narrow resonances with a mass of at least 1 TeV in the dijet mass spectrum is performed using pp collisions at Sqrt(s) = 7 TeV. View the MathML source corresponding to an integrated luminosity of 1 fb???1, collected by the CMS experiment at the LHC. No resonances are observed. Upper limits at the 95% confidence level are presented on the product of the resonance cross section, branching fraction into dijets, and acceptance, separately for decays into quark???quark, quark???gluon, and gluon???gluon pairs. The data exclude new particles predicted in the following models at the 95% confidence level: string resonances with mass less than 4.00 TeV, E6 diquarks with mass less than 3.52 TeV, excited quarks with mass less than 2.49 TeV, axigluons and colorons with mass less than 2.47 TeV, and W??? bosons with mass less than 1.51 TeV. These results extend previous exclusions from the dijet mass search technique.

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  • Indications of Suppression of Excited Upsilon States in Pb-Pb Collisions at root(NN)-N-s=2.76 TeV

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Goulianos, K; Lungu, G; Mesropian, C; Atramentov, O; Barker, A; Duggan, D; Gershtein, Y; Gray, R; Halkiadakis, E; Hidas, D; Hits, D; Lath, A; Panwalkar, S; Patel, R; Rose, K; Schnetzer, S; Somalwar, S; Stone, R; Thomas, S; Cerizza, G; Hollingsworth, M; Spanier, S; Yang, ZC; York, A; Eusebi, R; Flanagan, W; Gilmore, J; Gurrola, A; Kamon, T; Khotilovich, V; Montalvo, R; Osipenkov, I; Pakhotin, Y; Pivarski, J; Safonov, A; Sengupta, S; Tatarinov, A; Toback, D; Weinberger, M; Akchurin, N; Bardak, C; Damgov, J; Jeong, C; Kovitanggoon, K; Lee, SW; Libeiro, T; Mane, P; Roh, Y; Sill, A; Volobouev, I; Wigmans, R; Yazgan, E; Appelt, E; Brownson, E; Engh, D; Florez, C; Gabella, W; Issah, M; Johns, W; Kurt, P; Maguire, C; Melo, A; Sheldon, P; Snook, B; Tuo, S; Velkovska, J; Arenton, MW; Balazs, M; Boutle, S; Cox, B; Francis, B; Goodell, J; Hirosky, R; Ledovskoy, A; Lin, C; Neu, C; Yohay, R; Gollapinni, S; Harr, R; Karchin, PE; Lamichhane, P; Mattson, M; Ne, CM; Sakharov, A; Anderson, M; Bachtis, M; Bellinger, JN; Carlsmith, D; Dasu, S; Efron, J; Gray, L; Grogg, KS; Grothe, M; Hall-Wilton, R; Herndon, M; Herve, A; Klabbers, P; Klukas, J; Lanaro, A; Lazaridis, C; Leonard, J; Loveless, R; Mohapatra, A; Palmonari, F; Reeder, D; Ross, I; Savin, A; Smith, WH; Swanson, J; Weinberg, M (2011-07-28)

    Journal article
    The University of Auckland Library

    A comparison of the relative yields of Upsilon resonances in the mu(+)mu(-) decay channel in Pb-Pb and pp collisions at a center-of-mass energy per nucleon pair of 2.76 TeV is performed with data collected with the CMS detector at the LHC. Using muons of transverse momentum above 4 GeV/c and pseudorapidity below 2.4, the double ratio of the Upsilon(2S) and Upsilon(3S) excited states to the Upsilon(1S) ground state in Pb-Pb and pp collisions, [Upsilon(2S + 3S)/Upsilon(1S)](Pb-Pb) /[Upsilon 2S + 3S)/Upsilon(1S)](pp), is found to be 0.31(-0.15)(+0.19) (stat_ +/- 0.03(syst). The probability to obtain the measured value, or lower, if the true double ratio is unity, is calculated to be less than 1%.

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  • Refractive error and presbyopia in timor-leste: the impact of 5 years of a national spectacle program

    Ramke, Jacqueline; Brian, G; Naduvilath, T (2012-01)

    Journal article
    The University of Auckland Library

    To characterize refractive error, presbyopia, and spectacle correction among adults aged ???40 years in Timor-Leste in 2010 and examine the impact of the National Spectacle Program by comparing results to those obtained 5 years earlier.

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  • Chiral Br??nsted Acid-Catalyzed Enantioselective Multicomponent Mannich Reaction: Synthesis of anti-1,3-Diamines Using Enecarbamates as Nucleophiles

    Dagousset, G; Drouet, Fleur; Masson, G; Zhu, J (2009)

    Journal article
    The University of Auckland Library

    Reaction of aldehydes 2, anilines 3, and enecarbamates 4 in dichloromethane in the presence of EtOH and a catalytic amount of chiral phosphoric acid 5 afforded the Mannich adducts which were in situ reduced to anti-1,2-disubstituted 1,3-diamines 1 in excellent diastereoselectivity and enantioselectivity.

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  • Global and regional mortality from ischaemic heart disease and stroke attributable to higher-than-optimum blood glucose concentration: comparative risk assessment

    Danaei, G; Lawes, Carlene; Vander Hoorn, S; Murray, CJ; Ezzati, M (2006)

    Journal article
    The University of Auckland Library

    Summary Background Cardiovascular mortality risk increases continuously with blood glucose, from concentrations well below conventional thresholds used to de??? ne diabetes. We aimed to quantify population-level e??? ects of all higher-than-optimum concentrations of blood glucose on mortality from ischaemic heart disease and stroke worldwide. Methods We used population distribution of fasting plasma glucose to measure exposure to higher-than-optimum blood glucose. We collated exposure data in 52 countries from individual-level records in population health surveys, systematic reviews, and data provided by investigators. Relative risks for ischaemic heart disease and stroke mortality were from a meta-analysis of more than 200 000 participants in the Asia-Paci??? c region, with adjustment for other cardiovascular risk factors. Results In addition to 959 000 deaths directly assigned to diabetes, 1 490 000 deaths from ischaemic heart disease and 709 000 from stroke were attributable to high blood glucose, accounting for 21% and 13% of all deaths from these conditions. 1??8 million of these 2??2 million cardiovascular deaths (84%) were in low-and-middle-income countries (1 224 000 for ischaemic heart disease, 623 000 for stroke). 792 000 (53%) of deaths from ischaemic heart disease and 345 000 (49%) from stroke that were attributable to high blood glucose were in men. Largest numbers of deaths attributable to this risk factor from ischaemic heart disease were in low-and-middle-income countries of South Asia (548 000) and Europe and Central Asia (313 000), and from stroke in South Asia (215 000) and East Asia and Paci??? c (190 000). Interpretation Higher-than-optimum blood glucose is a leading cause of cardiovascular mortality in most world regions. Programmes for cardiovascular risk and diabetes management and control at the population level need to be more closely integrated.

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  • Experimental study of uplift loads due to tsunami bore impact on a wharf model

    Chen, C; Melville, Bruce; Nandasena, Napayalage; Shamseldin, Asaad; Wotherspoon, Liam (2016-11)

    Journal article
    The University of Auckland Library

    Tsunamis are unpredictable disasters that have occurred frequently in recent years. An experimental study was conducted to quantify the tsunami bore uplift loads on a deck mounted on a slope, representing a typical wharf structure. Tsunami bores were generated as dam break waves in a flume, and the bore Froude number was approximately 1.6 on the dry bed. Fifty-five tests (11 bore cases, 5 runs each cases) were conducted for detailed measurements of bore height and bore velocity, and 504 tests (7 bore cases, 3 deck heights, 8 wharf slope angles, 3 runs each combination) were conducted for measurements of time-histories of pressure on the soffit of the deck. The effects of bore height, deck height and slope angle on uplift loads were studied. Results show that bore height correlates with bore velocity. The flow motion of the tsunami bore impacting the deck is divided into five stages: front-climbing, front-hitting, run-up, quasi-steady, and recession. The uplift pressure decreases from the deck-slope connection to the deck front edge, and the total uplift load increases with increasing bore height or decreasing deck height. For the front-hitting stage (the maximum pressure), the uplift load increases as the wharf slope angle decreases. However, for the quasi-steady stage (the longest time period), the uplift load is consistent for different wharf slope angles. Based on the experimental data, the equations for predicting the front-hitting and quasi-steady pressures are proposed as functions of bore height, deck height and wharf slope angle, and the predicted values are within ?? 20% error.

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  • The distribution of the growth factors FGF-2 and VEGF, and their receptors, in growing red deer antler

    Lai, AK; Hou, Weilin; Verdon, Daniel; Nicholson, Louise; Barling, Peter (2007)

    Journal article
    The University of Auckland Library

    The cellular distributions of the growth factors FGF-2 and VEGF, and their receptors FGFR1, FGFR2 and FGFR3, and VEGFR-2 respectively, were visualized by immunohistochemistry and light microscopy in sections of growing red deer antler. Both of these signalling systems were widely expressed in the integument and osteocartilaginous compartments. FGF-2 was found in the same cells as all three FGFRs, indicating that FGF signalling may be principally autocrine. The patterns of labelling for VEGF and its receptor were similar to those seen for FGF-2 and FGFR-3, in both compartments. Our data are consistent with the findings of others in suggesting that FGF-2 induces expression of VEGF, to stimulate and maintain high rates of neovascularisation and angiogenesis, thereby providing nutrients to both velvet and bone as they rapidly grow and develop. The presence of FGF and VEGF and their receptors in epithelial cells suggests that these signalling systems play a role in skin development, raising the possibility that one or both may be involved in the close coupling of the coordinated growth of the integument and osteocartilage of antler, a process which is poorly understood at present.

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