45 results for Patent, 2010

  • Improvements for Cochlear Implants

    Bradley, AP; Petoe, Matthew; Wilson, WJ (2010)

    Patent
    The University of Auckland Library

    The invention relates to a method of generating a place-frequency map for accurate positioning of a cochlear implant whereby the place-frequency map is used to relate a physical position of the cochlear implant to a tonotopic map of the basilar membrane/spiral ganglion. The invention also relates to a method of electrically positioning of an already inserted cochlear implant within the cochlea to provide stimuli to only the parts of the cochlea that have reduced or no residual hearing.

    View record details
  • Dielectric elastomer self-sensing using plane approximation

    O'Brien, BM; Gisby, TA; Anderson, IA (2011)

    Patent
    The University of Auckland Library

    The present invention provides a method for obtaining feedback parameters related to the state of a dielectric elastomer (DE). The method comprises introducing a small-scale oscillation to the voltage difference between electrodes of the DE, monitoring or repeatedly measuring several measurable electrical characteristics of the DE, deriving other relevant data from the measurements, deriving an equation for a plane of best fit through the relevant data when defined as orthogonal axes, and deriving the feedback parameters from coefficients of the plane equation. The method thus provides important feedback regarding the capacitance, leakage current and/or electrode resistance of the DE. Also disclosed are a computer program and a system adapted to perform the method.

    View record details
  • Insecticidal Polypeptides and Methods of Use Thereof

    King, GF; Solld McFarland, B; Nicholson, GM; Gunning, Simon (2011-02-01)

    Patent
    The University of Auckland Library

    A family of insecticidal polypeptides expressed in the venom gland of spiders of the genera Atrax and Hadronyche have been described. Also included are polynucleotides and expression vectors encoding the polypeptides and insect viruses and cells expressing the polypeptides. Transgenic plants and insects expressing the insecticidal polypeptides are also described. The insecticidal polypeptides may be employed in methods and compositions for treating insects, insect larvae, and plants.

    View record details
  • Embryo modification and implantation.

    Blake, Deborah; Carter, NL; Henry, SM (2010-10-26)

    Patent
    The University of Auckland Library

    The present invention relates to constructs and methods used to enhance the attachment and implantation of an embryo. It is shown that modified glycolipids and glycolipid-attachment molecule constructs can be used to modify embryos, or localised to target tissues, to enhance interaction between the embryo and the target tissue, (typically the endometrium). The invention may advantageously be used to enhance implantation of embryos in the uterus, for example, in IVF treatments.

    View record details
  • Conducting polymer nanowire brain-machine interface systems and methods

    Llinas, RR; Hunter, IW; Ruddy, BP (2011)

    Patent
    The University of Auckland Library

    The present invention relates to conducting polymer nanowires and their use in a brain-machine interface which is secure, robust and minimally invasive. In accordance with a first aspect of the present invention, a vascular-based brain-machine interface comprising conducting polymer nanowires is disclosed.

    View record details
  • 1,2,4-benzotriazine-1,4-dioxides

    Denny, William; Hay, Michael; Hicks, Kevin; Pruijn, Frederik; Wilson, William; Pchalek, Karin (2010)

    Patent
    The University of Auckland Library

    View record details
  • Methods for producing neuronal cells and uses thereof

    Green, Colin; Sherwin, Trevor; Chang, CYA (2010)

    Patent
    The University of Auckland Library

    Methods for producing neuronal cells, methods of treating or preventing ophthalmic diseases or conditions or of promoting recovery from an ophthalmic therapy, and methods of treating or preventing neurological diseases or conditions or of promoting recovery from a neurological therapy are provided. The methods involving treating ophthalmic cells, particularly corneal cells, with insulin, epidermal growth factor and fibroblast growth factor 2 for a period sufficient to trans-differentiate the cells to neuronal cells.

    View record details
  • Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer Therapy

    Rewcastle, Gordon; Gamage, Swarnalatha; Flanagan, JU; Giddens, Anna; Tsang, KY (2013-06-11)

    Patent
    The University of Auckland Library

    Provided herein are pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides, e.g. compounds of Formula 1A, 1B, and 1C, and their pharmaceutical compositions, preparation, and use as agents or drugs for cancer therapy, either alone or in combination with radiation and/or other anticancer drugs.

    View record details
  • Kinase inhibitors, prodrug forms thereof and their use in therapy.

    Smaill,, JB; Patterson, AV; Lu, G-L; Lee, Ho; Ashoorzadeh, A; Anderson, RF; Wilson, WR; Denny, WA; Hsu, A; Maroz, A; Jamieson, SMF; Mowday, AM; Carlin, KM (2011-03-10)

    Patent
    The University of Auckland Library

    The present invention relates to pyrido[3,4-d]pyrimidine compounds of formula (I) suitable as kinase inhibitors, kinase inhibitors in prodrug form, their use in compositions and medicaments which are suitable for the treatment of diseases related to kinase activity such as cancers.

    View record details
  • Conducting polymer nanowire brain-machine interface systems and methods

    Llinas, RR; Hunter, IW; Ruddy, Bryan (2010-10-19)

    Patent
    The University of Auckland Library

    The present invention relates to conducting polymer nanowires and their use in a brain-machine interface which is secure, robust and minimally invasive. In accordance with a first aspect of the present invention, a vascular-based brain-machine interface comprising conducting polymer nanowires is disclosed.

    View record details
  • Contact lens and method for prevention of myopia progression

    Phillips, John (2011)

    Patent
    The University of Auckland Library

    A method of slowing the progression of myopia in a person, comprises applying to the eye of the person contact lens or lenses each including a vision correction area for correcting in use the myopic vision of a wearer, and a myopic defocus area having a less negative focal power, to simultaneously present a controlled myopic defocus to the retina both when viewing in the distance and also when viewing at near. Contact lenses and their use are also claimed.

    View record details
  • Methods and compositions for increasing storage-life of fruit

    Atkinson, R; Schaffer, Robert; Gunaseelan, K; Schroeder, R (2010)

    Patent
    The University of Auckland Library

    The invention provides methods and compositions for producing plants with fruit having increased post-harvest storage life, the method comprising reducing the expression or activity in the plant, of a polypeptide with the amino acid sequence of SEQ ID NO: 1(Malus domestica polygalaturonase, MdPG1), or a variant of the polypeptide. The invention provides host cells, plant cells and plants transformed with the polynucleotides of the invention. The invention also provides methods for selecting plants with fruit having increased postharvest storage life. The invention also provides plants produced and selected by the methods of the invention.

    View record details
  • Pyrimidinyl and 1,3,5-triazinyl benzimidazoles and their use in cancer therapy

    Rewcastle, Gordon; Tsang, KY; Gamage, Swarnalatha; Giddens, Anna (2013-07-16)

    Patent
    The University of Auckland Library

    Provided herein are pyrimidinyl and 1,3,5-triazinyl benzimidazoles of Formula I, and their pharmaceutical compositions, preparation, and use as agents or drugs for cancer therapy, either alone or in combination with radiation and/or other anticancer drugs.

    View record details
  • Conducting polymer nanowire brain-machine interface systems and methods

    Llinas, RR; Hunter, IW; Ruddy, Bryan (2013-03-26)

    Patent
    The University of Auckland Library

    The present invention relates to conducting polymer nanowires and their use in a brain-machine interface which is secure, robust and minimally invasive. In accordance with a first aspect of the present invention, a vascular-based brain-machine interface comprising conducting polymer nanowires is disclosed.

    View record details
  • Needle-free injector device with autoloading capability

    Hunter, IW; Hemond, BD; Wendell, DM; Hogan, NC; Taberner, Andrew; Ball, NB (2014-03-25)

    Patent
    The University of Auckland Library

    A needle-free transdermal transport device includes a chamber (900) for holding the substance to be injected, a nozzle (910) in fluid communication with the chamber, and a drug reservoir (950) for storing the substance to be transferred to the chamber. The needle-free transdermal transport device also includes a controllable magnet and coil electromagnetic actuator (242) in communication with the chamber. The actuator receives an electrical input and generates in response a force. The force then causes a needle-free transfer of the substance from the chamber to the biological body. The force is variable responsive to variations in the received input during actuation. The actuator draws the substance from the drug reservoir or alternatively, the substance can be pressurized from the drug reservoir into the chamber by a pressure source.

    View record details
  • Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate

    Gluckman, Peter; Brimble, Margaret; Wilson, D; Tortella, FC; Williams, AJ; Xi-Chun, ML; Hartings, JA; Gryder, D (2010-05-11)

    Patent
    The University of Auckland Library

    Aspects of this invention include the use of G-2MePE to treat patients with brain injury characterized by non-convulsive seizures. G-2MePE is useful in treating brain injuries caused by traumatic brain injury, stroke, hypoxia/ischemia and toxic injury.

    View record details
  • Transcription factors

    Bloksberg, LN; Bryant, C; Connett, MB; Emerson, SJ; Forster, RLS; Frost, J; Gause, K; Grigor, M; Havukkala, I; Higgins, C; Lasham, Annette; Lund, ST; Magusin, A; Phillips, J; Puthigae, S; Rottmann, WH; Veerakone, S; Westwood, C; Wood, M (2012)

    Patent
    The University of Auckland Library

    The invention provides polynucleotide sequences isolated from plants encoding transcription factors. Polypeptides encoded by the polynucleotides are also provided. Products and methods of use are disclosed.

    View record details
  • Impaired wound healing compositions and treatments

    Becker, DL; Green, Colin; Duft, BJ (2011-11-22)

    Patent
    The University of Auckland Library

    Methods, compounds, compositions, kits and articles of manufacture comprising one or more gap junction modulating agents for treatment of wounds that do not heal at expected rates, including chronic wounds, delayed healing wounds, incompletely healing wounds, and dehiscent wounds in a subject in need thereof.

    View record details
  • Selection of animals for desired milk and/or tissue profile

    Lehnert, K; Berry, SD; Snell, Russell; Macgibbon, AKH; Spelman, R; Ankermist-Udy, A (2011)

    Patent
    The University of Auckland Library

    The present invention is directed to mutations in the DGAT1 gene that produce an advantageous milk, tissue and/or growth rate profile in animals carrying the mutations. The present invention is also directed to methods of identifying animals carrying the mutations in order to facilitate the selection of animals with altered milk, tissue and/or growth rate traits.

    View record details
  • Directly photodefinable polymer compositions and methods thereof

    Elce, E; Bell, A; Knapp, B; Ng, H; Rhodes, LF; Shick, R; Zhang, W; Dimenna, W; Jayaraman, S; Jin, Jianyong; Puthenkovilakom, RR; Ravikiran, R; Wu, X; Takeuchi, E (2011)

    Patent
    The University of Auckland Library

    A polymer includes a first type of repeat unit represented by Formula I, where X is selected from -CH2-, -CH2-CH2-, or -O-; m is an integer from 0 to about 5; and where for the first type of repeat unit one of R1, R2, R3, and R4 is one of a maleimide containing group and for the second type of repeat unit one of R1, R2, R3, and R4 is a hindered aromatic group, a C8 or greater alkyl group, a C4 or greater halohydrocarbyl or perhalocarbyl group, a C7 or greater aralkyl group, or a heteroatom hydrocarbyl or halohydrocarbyl group.

    View record details