79 results for Patent, All rights reserved

  • Novel food product and method of use

    Johnson, PS; Lee, S; Altalhi, ASD

    Patent
    Massey University

    The invention includes a composition when used for the subsequent preparation of an egg white foam, characterised in that the composition includes an amount of egg white material and at least one thickener. The amount of thickener(s) is at least about 2.0%w/w in the composition and the composition has been heat treated at or above about 40°Cprior to preparing the egg white foam. The invention also encompasses method of use, novel food products, cooked or uncooked, and methods of manufacture.

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  • In-situ optical density sensor

    Harrison, JA; Saraswat, M; Grand, R; Noble, FK; Gehlen, L; Woods, MA; Bartho, S

    Patent
    Massey University

    The present invention relates to optical measurement devices and systems, and methods of using these systems and devices, and more particularly but not exclusively it relates to a system and apparatus adapted to measure optical properties in-situ.

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  • Pyrazolo[1,5-a]pyridines and their use in cancer therapy

    Kendall, JD; Marshall, Andrew (2009)

    Patent
    The University of Auckland Library

    Phosphoinositide-3-kinases (PI3Ks) are a group of lipid kinases which phosphorylate the 10 3-hydroxyl of phosphoinositides. They are split into three classes (Class I, II and Ill) and play an important role in cellular signalling [Stephens et al., Curr. Opin. Pharmacal. 2005, 5, 357]. The Class I enzymes are further split into Class Ia and lb based on their mechanism of activation; the Class Ia PI3Ks are heterodimeric structures consisting of a catalytic subunit (p11 Oa, p11 013 or p11 0~) in complex with a regulatory p85 subunit, while 15 the class-IB PI3K (p11 Oy) is structurally similar but lacks a reguiatory subunit linking and instead is activated by 13v subunits of heterotrimeric G-proteins [Walker et al,. Moi.Ce/1., 2000, 6, 909]. PI3Ks play a variety of roles in normal tissue physiology [Foukas & Shepherd, Biochem. 20 Soc. Trans., 2004,32, 330; Shepherd,Acta Physiol. Scand,. 2005, 183, 3], with p110a having a specific role in cancer growth, p11 013 in thrombus formation mediated by integrin aul33 [Jackson et al., Nat. Med., 2005, 11, 507], and p11 Oy in inflammation, rheumatoid arthritis [Camps et al., Nat. Med., 2005, 11, 936] and other chronic inflammation states [Barber et al., Nat. Med., 2005, 11, 933]. The PI3K enzymes produce phosphoinositide 25 3,4,5-triphosphate (PIP3) from the corresponding diphosphate (PIP2), thus recruiting AKT (protein kinase B) through its PH domain, to the plasma membrane. Once bound, AKT is phosphorylated and activated by other membrane bound kinases, and is central to a cascade of events that lead to inhibition of apoptosis [Berrie, Exp. Opin. Invest. Drugs, 2001, 10, 1085].

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  • Quinoline derivatives for modulating DNA methylation.

    Brooke, Darby; Phiasivongsa, P; Denny, WA; Gamage, S; Bearss, DJ; Vankayalapati, H; Redkar, SG (2009)

    Patent
    The University of Auckland Library

    (EN)Quinoline derivatives, particularly 4-anilinoquinoline derivatives, are provided. Such quinoline derivatives can be used for modulation of DNA methylation, such as effective inhibition of methylation of cytosine at the C-5 position, for example via selective inhibition of DNA methyltransferase DNMT1. Methods for synthesizing numerous 4-anilinoquinoline derivatives and for modulating DNA methylation are provided. Also provided are methods for formulating and administering these compounds or compositions to treat conditions such as cancer and hematological disorders. (FR)Cette invention concerne des dérivés de quinoline, en particulier des dérivés de 4-anilinoquinoline. Ces dérivés de quinoline peuvent être utilisés dans la modulation de la méthylation de l'ADN, par exemple dans l'inhibition effective de la méthylation de la cytosine en position C-5, par exemple par une inhibition sélective de l'ADN méthyltransférase DNMT1. L'invention concerne par ailleurs des procédés permettant de synthétiser plusieurs dérivés de 4-anilinoquinoline et de moduler la méthylation de l'ADN. L'invention concerne également des procédés permettant de formuler et d'administrer ces composés ou ces compositions pour traiter des pathologies comme le cancer et les troubles hématologiques.

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  • Diagnostically and audibly responsive computer learning memory game and system provided therefor

    Dowrick, Peter (2006)

    Patent
    The University of Auckland Library

    A diagnostically and audibly responsive computer learning memory game works with small children and other persons in teaching them to read. Square or rectangular tiles to be uncovered are displayed upside down, concealing words to be matched with words or words to be matched with phrases or visual pictures or audible sounds, objective is to find matching cards. The computer game matches the cards or tiles with sight words that the user is learning to read from a word list. The user must remember where a correct word of the word pairs is located. The user must read word orally, if not, the computer will prompt the user with a clue (such as the beginning sound of a word) until the user answers. If nothing is heard, the user is told the answer. The system has a built-in recording of a library of selected words, phrases, pictures or audible sounds. The computer can sense that user is silent (with a default of no sound). If a wrong word is uttered, the system can remain silent or correct..

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  • Polypeptides and Polynucleotides for Artemin and related Ligands, and Methods of Use Thereof

    Liu, Dongxu; Lobie, Peter (2008)

    Patent
    The University of Auckland Library

    The invention encompasses polypeptides, polynucleotides, and antibodies, for Artemin and related ligands, including Persephin (PSPN). The invention also encompasses expression vectors and host cells for producing these polypeptides, polynucleotides, or antibodies. The invention further encompasses diagnostics and therapeutics, especially for cancer, and particularly breast cancer, colon cancer, prostate cancer, endometrial cancer, lung cancer, stomach cancer, liver cancer, and others, comprising one or more of the disclosed polypeptides, polynucleotides, antibodies, expression vectors, host cells, or compositions thereof. Particularly encompassed are inhibitors of Artemin and/or related ligands, and uses for these inhibitors.

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  • Improvements for Cochlear Implants

    Bradley, AP; Petoe, Matthew; Wilson, WJ (2010)

    Patent
    The University of Auckland Library

    The invention relates to a method of generating a place-frequency map for accurate positioning of a cochlear implant whereby the place-frequency map is used to relate a physical position of the cochlear implant to a tonotopic map of the basilar membrane/spiral ganglion. The invention also relates to a method of electrically positioning of an already inserted cochlear implant within the cochlea to provide stimuli to only the parts of the cochlea that have reduced or no residual hearing.

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  • Dielectric elastomer self-sensing using plane approximation

    O'Brien, BM; Gisby, TA; Anderson, IA (2011)

    Patent
    The University of Auckland Library

    The present invention provides a method for obtaining feedback parameters related to the state of a dielectric elastomer (DE). The method comprises introducing a small-scale oscillation to the voltage difference between electrodes of the DE, monitoring or repeatedly measuring several measurable electrical characteristics of the DE, deriving other relevant data from the measurements, deriving an equation for a plane of best fit through the relevant data when defined as orthogonal axes, and deriving the feedback parameters from coefficients of the plane equation. The method thus provides important feedback regarding the capacitance, leakage current and/or electrode resistance of the DE. Also disclosed are a computer program and a system adapted to perform the method.

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  • Novel Saratan Polypeptides and Polynucleotides and Methods of Use Thereof

    Liu, Dongxu; Lobie, Peter (2008)

    Patent
    The University of Auckland Library

    The invention relates to Saratan polypeptides, polynucleotides, and antibodies. The invention also relates to expression vectors and host cells for producing these polypeptides, polynucleotides, or antibodies. The invention further relates to diagnostics and therapeutics, especially for cancer, and particularly breast cancer, comprising one or more of the disclosed polypeptides, polynucleotides, antibodies, expression vectors, host cells, or compositions thereof.

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  • Insecticidal Polypeptides and Methods of Use Thereof

    King, GF; Solld McFarland, B; Nicholson, GM; Gunning, Simon (2011-02-01)

    Patent
    The University of Auckland Library

    A family of insecticidal polypeptides expressed in the venom gland of spiders of the genera Atrax and Hadronyche have been described. Also included are polynucleotides and expression vectors encoding the polypeptides and insect viruses and cells expressing the polypeptides. Transgenic plants and insects expressing the insecticidal polypeptides are also described. The insecticidal polypeptides may be employed in methods and compositions for treating insects, insect larvae, and plants.

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  • Embryo modification and implantation.

    Blake, Deborah; Carter, NL; Henry, SM (2010-10-26)

    Patent
    The University of Auckland Library

    The present invention relates to constructs and methods used to enhance the attachment and implantation of an embryo. It is shown that modified glycolipids and glycolipid-attachment molecule constructs can be used to modify embryos, or localised to target tissues, to enhance interaction between the embryo and the target tissue, (typically the endometrium). The invention may advantageously be used to enhance implantation of embryos in the uterus, for example, in IVF treatments.

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  • Conducting polymer nanowire brain-machine interface systems and methods

    Llinas, RR; Hunter, IW; Ruddy, BP (2011)

    Patent
    The University of Auckland Library

    The present invention relates to conducting polymer nanowires and their use in a brain-machine interface which is secure, robust and minimally invasive. In accordance with a first aspect of the present invention, a vascular-based brain-machine interface comprising conducting polymer nanowires is disclosed.

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  • Breathing Assistance Apparatus

    Shahbazpour, Mehdi; Troudsell, MJB; Nightingale, CE; McAuley, AE; Shotbolt, AM (2006)

    Patent
    The University of Auckland Library

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  • 1,2,4-benzotriazine-1,4-dioxides

    Denny, William; Hay, Michael; Hicks, Kevin; Pruijn, Frederik; Wilson, William; Pchalek, Karin (2010)

    Patent
    The University of Auckland Library

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  • Controlled needle-free transport

    Hunter, IW; Taberner, Andrew; Hemond, BD; Wendell, DM; Ball, NB; Hogan, NC

    Patent
    The University of Auckland Library

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  • Compositions and Methods for Regulating Plant Gene Expression

    Espley,, RV; Hellens,, RP; Allan,, AC; Chagn??,, D (2008)

    Patent
    The University of Auckland Library

    The invention provides a method for producing a chimeric promoter polynucleotide capable of controlling transcription of an operably linked polynucleotide in a plant cell or plant, wherein the method comprises combining: a) at least one sequence motif comprising a sequence with at least 70% identity to SEQ ID NO:1, 11 or 12, and b) another polynucleotide sequence. The invention also provides chimeric promoters polynucleotides comprising the sequences defined in a) and b). The invention also provides constructs, vectors, host cells, plant cells and plants comprising the chimeric promoter polynucleotides of the invention. The invention also provided methods for modifying gene expression and phenotype of plant cells and plants by transforming the plant cells and plants with the chimeric promoter polynucleotides of the invention.

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  • Cascaded Raman Laser

    Martinelli, C; Leplingard, F; Sylvestre, T; Vanholsbeeck, Frederique; Emplit, P (2006-02-07)

    Patent
    The University of Auckland Library

    A cascaded Raman laser (10) has a pump radiation source (12) emitting at a pump wavelength ??p, an input section (14) and an output section (16) made of an optical medium. Each section (14, 16) comprises wavelength selectors (141, 142, . . . , 145 and 161, 162, . . . , 165) for wavelengths ??1, ??2, . . . , ??n???k, where n???3, ??p?1?2< . . . ?n???1?n and ??n???k+1, ??n???k+2, . . . , ??n being k???1 emitting wavelengths of the laser (10). The laser further comprises an intracavity section (18) that is made of a non-linear optical medium, has a zero-dispersion wavelength ??0 and is disposed between the input (14) and the output (16) section. The wavelengths ??1, ??2, . . . , ??n???k of the wavelength selectors (141, 142, . . . , 145 and 161, 162, . . . , 165) and the zero-dispersion wavelength ??0 of the intracavity section (18) are chosen such that energy is transferred between different wavelengths by multi-wave mixing.

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  • Methods for producing neuronal cells and uses thereof

    Green, Colin; Sherwin, Trevor; Chang, CYA (2010)

    Patent
    The University of Auckland Library

    Methods for producing neuronal cells, methods of treating or preventing ophthalmic diseases or conditions or of promoting recovery from an ophthalmic therapy, and methods of treating or preventing neurological diseases or conditions or of promoting recovery from a neurological therapy are provided. The methods involving treating ophthalmic cells, particularly corneal cells, with insulin, epidermal growth factor and fibroblast growth factor 2 for a period sufficient to trans-differentiate the cells to neuronal cells.

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  • 5-Substituted-4-[(substituted phenyl)amino]-2-pyridone derivatives

    Black, Shannon; Kaufman, MD; Ortwine, DF; Plummer, MS; Quin, J; Rewcastle, Gordon; Shahripour, AB; Spicer, Julie; Whitehead, CE (2007)

    Patent
    The University of Auckland Library

    The present invention relates to 5-substituted-4-(substituted)phenylamino-2-pyridone derivatives, pharmaceutical compositions and methods of use thereof.

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  • Pteridinones as kinase inhibitors

    Denny, William; Rewcastle, Gordon; Dobrusin, EM; Kramer, JB; McNamara, DJ; Showalter, HD; Toogood, PL (2007)

    Patent
    The University of Auckland Library

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