79 results for Patent

  • Needle-free injector device with autoloading capability

    Hunter, IW; Hemond, BD; Wendell, DM; Hogan, NC; Taberner, Andrew; Ball, NB (2014-03-25)

    Patent
    The University of Auckland Library

    A needle-free transdermal transport device includes a chamber (900) for holding the substance to be injected, a nozzle (910) in fluid communication with the chamber, and a drug reservoir (950) for storing the substance to be transferred to the chamber. The needle-free transdermal transport device also includes a controllable magnet and coil electromagnetic actuator (242) in communication with the chamber. The actuator receives an electrical input and generates in response a force. The force then causes a needle-free transfer of the substance from the chamber to the biological body. The force is variable responsive to variations in the received input during actuation. The actuator draws the substance from the drug reservoir or alternatively, the substance can be pressurized from the drug reservoir into the chamber by a pressure source.

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  • Method and system of measuring charateristics of an organ

    Young, Alistair; Cowan, Brett (2006-12-26)

    Patent
    The University of Auckland Library

    The invention provides a method of measuring characteristics of an organ or part thereof from multiple images of the organ or part thereof, the method comprising the steps of defining the spatial position of at least two of the images; defining a reference model of the organ or part thereof scaled according to the distance between reference markers on the images; defining one or more boundary guide points associated with one or more images for which the spatial positions have been defined; converting the guide points to three-dimensional coordinates; defining an estimate model by fitting the reference model to the guide points; and calculating the characteristics from the estimate model. The invention also provides a system and a computer program for measuring characteristics of an organ or part thereof of a subject from multiple images of the subject's organ or part thereof.

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  • Insecticidal Polypeptides and Methods of Use Thereof

    King, GF; Solld McFarland, B; Nicholson, GM; Gunning, Simon (2011-02-01)

    Patent
    The University of Auckland Library

    A family of insecticidal polypeptides expressed in the venom gland of spiders of the genera Atrax and Hadronyche have been described. Also included are polynucleotides and expression vectors encoding the polypeptides and insect viruses and cells expressing the polypeptides. Transgenic plants and insects expressing the insecticidal polypeptides are also described. The insecticidal polypeptides may be employed in methods and compositions for treating insects, insect larvae, and plants.

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  • System and method for mapping gastro-intestinal electrical activity.

    O'Grady, Gregory; Cheng, LK; Pullan, AJ; Du, P; Erickson, JC (2011)

    Patent
    The University of Auckland Library

    A gastro-electrical activity mapping system and comprises a catheter insertable through a natural orifice into the gastro-intestinal (GI) tract and comprising an array of electrodes for contacting an interior surface of a section of the GI tract to detect electrical potentials at multiple electrodes, and a signal analysis and mapping system arranged to receive and process electrical signals from multiple electrodes of the array and spatially map GI smooth muscle electrical activity as an activation time map, a velocity map, or an amplitude map, which may be in the form of contour plots and may be mapped on an anatomical computer model of at least the section of the GI tract and may be animated. A GI mapping method and catheter are also claimed.

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  • Kinase inhibitors, prodrug forms thereof and their use in therapy.

    Smaill,, JB; Patterson, AV; Lu, G-L; Lee, Ho; Ashoorzadeh, A; Anderson, RF; Wilson, WR; Denny, WA; Hsu, A; Maroz, A; Jamieson, SMF; Mowday, AM; Carlin, KM (2011-03-10)

    Patent
    The University of Auckland Library

    The present invention relates to pyrido[3,4-d]pyrimidine compounds of formula (I) suitable as kinase inhibitors, kinase inhibitors in prodrug form, their use in compositions and medicaments which are suitable for the treatment of diseases related to kinase activity such as cancers.

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  • Tinnitus treatment system and method

    Searchfield, Grant; Kobayashi, Kei; Irving, Samuel (2011)

    Patent
    The University of Auckland Library

    A tinnitus masking system for use by a person having tinnitus. The system comprises a sound delivery system having left and right ear-level audio delivery devices and is configured to deliver a masking sound to the person via the audio delivery devices such that the masking sound appears to originate from a virtual sound source location that substantially corresponds to the spatial location in 3D auditory space of the source of the tinnitus as perceived by the person. The masking sound being represented by left and right audio signals that are converted to audible sound by the respective audio delivery devices.

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  • Embryo modification and implantation.

    Blake, Deborah; Carter, NL; Henry, SM (2010-10-26)

    Patent
    The University of Auckland Library

    The present invention relates to constructs and methods used to enhance the attachment and implantation of an embryo. It is shown that modified glycolipids and glycolipid-attachment molecule constructs can be used to modify embryos, or localised to target tissues, to enhance interaction between the embryo and the target tissue, (typically the endometrium). The invention may advantageously be used to enhance implantation of embryos in the uterus, for example, in IVF treatments.

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  • Conducting polymer nanowire brain-machine interface systems and methods

    Llinas, RR; Hunter, IW; Ruddy, Bryan (2010-10-19)

    Patent
    The University of Auckland Library

    The present invention relates to conducting polymer nanowires and their use in a brain-machine interface which is secure, robust and minimally invasive. In accordance with a first aspect of the present invention, a vascular-based brain-machine interface comprising conducting polymer nanowires is disclosed.

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  • Heat Exchanger

    Taylor, Mark; Chen, John; Farid, M; Wallace, RJ (2014-07-15)

    Patent
    The University of Auckland Library

    A heat exchanger 10 includes a conduit 12 for conveying cooling fluid relative to a body to be cooled. A heat transfer arrangement 62 is arranged in communication with an interior of the conduit 12, the heat transfer arrangement 62 and the conduit 12 together defining an assembly that is mountable adjacent the body to be cooled, convective heat exchange occurring, in use, due to movement of the cooling fluid relative to the body and to the heat transfer arrangement 62 of the assembly and radiant heat exchange occurring between the body and at least part of the heat transfer arrangement 62 of the assembly.

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  • Gastric Therapies and Compositions Thereof

    Roberton, AM; O'Connor, Charmian; Martin, Iain; Alany, Raid (2008)

    Patent
    The University of Auckland Library

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  • Pyrimidinyl and 1,3,5-triazinyl benzimidazoles and their use in cancer therapy

    Rewcastle, Gordon; Tsang, KY; Gamage, Swarnalatha; Giddens, Anna (2013-07-16)

    Patent
    The University of Auckland Library

    Provided herein are pyrimidinyl and 1,3,5-triazinyl benzimidazoles of Formula I, and their pharmaceutical compositions, preparation, and use as agents or drugs for cancer therapy, either alone or in combination with radiation and/or other anticancer drugs.

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  • Conducting polymer nanowire brain-machine interface systems and methods

    Llinas, RR; Hunter, IW; Ruddy, Bryan (2013-03-26)

    Patent
    The University of Auckland Library

    The present invention relates to conducting polymer nanowires and their use in a brain-machine interface which is secure, robust and minimally invasive. In accordance with a first aspect of the present invention, a vascular-based brain-machine interface comprising conducting polymer nanowires is disclosed.

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  • GPE Analogs and Peptidomimetics

    Abood, NA; Brimble, Margaret (2003-03-20)

    Patent
    The University of Auckland Library

    This invention relates to analogs and peptidomimetics of glycyl-L-prolyl-L-glutamic acid (GPE). In particular, this invention relates to GPE analogs and peptidomimetics that are anti-apoptotic and anti-necrotic, to methods of making them, to pharmaceutical compositions containing them, and to their use.

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  • Neuroprotective Bicyclic Compounds and Methods for their Use

    Brimble, Margaret; Guan, Jian; Sieg, Frank (2005-03-17)

    Patent
    The University of Auckland Library

    Embodiments of this invention provide novel cyclic compounds structurally related to diketopiperazines and methods for their therapeutic use. Such compounds are neuroprotective and have utility as therapeutic agents for treatment of diseases, injuries and other conditions characterised by neuronal degeneration and/or death. Compounds are also useful for manufacture of medicaments useful for treatment of such conditions.

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  • Adrenocorticotropic hormone analogs and related methods

    Brennan, MB; Costa, Jessica; Dores, RM; Hochgeschwender, U; Haskell-Luevano, C (2007)

    Patent
    The University of Auckland Library

    ACTH analog compounds of the present invention include compounds comprising an ACTH peptide sequence with one or more structural modifications that can have one or more of the following preferred ACTH analog biological functions: (1) reduction of corticosteroid secretion by adrenal membrane in the presence of the ACTH analog compared to unmodified ACTH, (2) reduction of corticosteroid secretion by adrenal membrane in the presence of endogenous ACTH and (3) increased MC-2R binding affinity with reduced activation of the MC-2R receptor compared to unmodified ACTH binding to the MC-2R melanocortin. The ACTH analog compounds of the present invention are therefore useful for treatment or prevention of diseases and disorders related to ACTH, ACTH receptors or corticosteroid secretion, such as premature labor and Cushing's Disease.

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  • System and method for tracking facial muscle and eye motion for computer graphics animation

    Sagar, Mark; Scott, R (2009)

    Patent
    The University of Auckland Library

    A motion tracking system enables faithful capture of subtle facial and eye motion using a surface electromyography (EMG) detection method to detect muscle movements and an electrooculogram (EOG) detection method to detect eye movements. An embodiment of the motion tracking animation system comprises a plurality of pairs of EOG electrodes adapted to be affixed to the skin surface of the performer at locations adjacent to the performer's eyes. The EOG data comprises electrical signals corresponding to eye movements of a performer during a performance. Programming instructions further provide processing of the EOG data and mapping of processed EOG data onto an animated character. As a result, the animated character will exhibit he same muscle and eye movements as the performer.

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  • Inductively Powered Mobile Sensor System

    Malpas, Simon; Hu, AP; Budgett, David (2004-09-16)

    Patent
    The University of Auckland Library

    The present invention provides an inductively powered sensor system having a primary conductive path capable of being energized to provide an electromagnetic field in a defined space. An inductive power pick-up is associated with a sensor and is capable of receiving power from the field to supply the sensor. The system includes a first sensing unit to sense the power available to the pick-up and a control unit to increase or decrease the power available to the sensor dependant on the sensed power available. A method of inductively powering a sensor, an inductively powered sensor and an animal enclosure including one or more primary conductive path of an inductive power supply are also disclosed.

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  • Cognitive Enhancement and Cognitive Therapy Using Glycyl-L-2-Methylprolyl-L-Glutamic Acid

    Gluckman, Peter; Guan, Jian; Woodworth, M; Brimble, Margaret

    Patent
    The University of Auckland Library

    This invention provides compounds, compositions and methods for treating loss of cognitive function in animals that results from aging. In particular, compounds of this invention can stimulate neural cell growth, increased amounts of cells containing a key enzyme needed for production of the cholinergic neurotransmitter, and can improve memory and cognitive function in animals who have experienced a loss of memory or cognitive function as a result of aging.

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  • Conducting polymer nanowire brain-machine interface systems and methods

    Llinas, RR; Hunter, IW; Ruddy, BP (2011)

    Patent
    The University of Auckland Library

    The present invention relates to conducting polymer nanowires and their use in a brain-machine interface which is secure, robust and minimally invasive. In accordance with a first aspect of the present invention, a vascular-based brain-machine interface comprising conducting polymer nanowires is disclosed.

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